There are 4 ways to get from Cape Girardeau to Columbia by bus (Greyhound), car, taxi, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Cape Girardeau to St Louis Bus Stationbus Greyhound US1173
- Take the bus from St Louis Bus Station to Columbiabus Greyhound US0175s
5h 54m$44–83Drive 223.3 mi
cheapest- Drive from Cape Girardeau to Columbiacar 223.3 mi
3h 54m$41–59Taxi to Williamson County Regional Airport, fly
- Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi
- Fly from Williamson County Regional Airport (MWA) to Columbia Regional Airport (COU)plane MWA - COU
6h 23m$263–672Taxi to Barkley Regional Airport, fly
- Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi
- Fly from Barkley Regional Airport (PAH) to Columbia Regional Airport (COU)plane PAH - COU
7h 2m$263–614
Williamson County Regional Airport (MWA) to Columbia Regional Airport (COU) flights
Questions & Answers
The cheapest way to get from Cape Girardeau to Columbia is to drive which costs $40 - $60 and takes 3h 54m.
The fastest way to get from Cape Girardeau to Columbia is to drive which takes 3h 54m and costs $40 - $60.
No, there is no direct bus from Cape Girardeau to Columbia. However, there are services departing from Cape Girardeau and arriving at Columbia via St Louis Bus Station. The journey, including transfers, takes approximately 5h 54m.
The distance between Cape Girardeau and Columbia is 259 miles. The road distance is 224.6 miles.
The best way to get from Cape Girardeau to Columbia without a car is to bus which takes 5h 54m and costs $40 - $85.
It takes approximately 5h 54m to get from Cape Girardeau to Columbia, including transfers.
Cape Girardeau to Columbia bus services, operated by Greyhound USA, depart from Cape Girardeau station.
Cape Girardeau to Columbia bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Cape Girardeau to Columbia is 225 miles. It takes approximately 3h 54m to drive from Cape Girardeau to Columbia.
Book your Cape Girardeau to Columbia bus tickets online with Omio.
What companies run services between Cape Girardeau, MO, USA and Columbia, MO, USA?
You can take a vehicle from Cape Girardeau to Columbia via Cape Girardeau and St Louis Bus Station in around 5h 54m.
- Website
- united.com
Flights from Williamson County Regional Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $80–450
Flights from Barkley Regional Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 7h 23m
- When
- Every day
- Estimated price
- $70–380
- Website
- aa.com
Flights from Williamson County Regional Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $80–450
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $16–35
- Website
- Greyhound
Bus from St Louis Bus Station to Columbia
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $21–40
- Website
- Greyhound
- Ave. Duration
- 1h 20m
- Estimated price
- $130–170
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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More Questions & Answers
There are 50+ hotels available in Columbia.


