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How to get fromCape Girardeau to Destinby bus, plane, taxi, train, or car

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There are 7 ways to get from Cape Girardeau to Destin by bus, plane, taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    5h 59m
    $151–551

  2. Drive  607.8 mi

    cheapest
    1. Drive from Cape Girardeau to Destincar car 607.8 mi
    11h 54m
    $104–151

  3. Taxi, train, bus

    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Pascagoulatrain train
    4. Take the bus from Pascagoula to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    22h 4m
    $623–927

  4. Bus, taxi

    1. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    2. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    3. Take the bus from Biloxi to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    22h 14m
    $256–378

  5. Bus to Midamerica St. Louis Airport, fly

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    6h 11m
    $159–509

  6. Taxi, bus to Nashville, fly

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Destin–Fort Walton Beach Airport (VPS)plane plane BNA - VPS
    8h 20m
    $235–619

  7. Fly from Cape Girardeau Municipal Airport

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Destin–Fort Walton Beach Airport (VPS)plane plane CGI - VPS
    21h 53m
    $159–553

Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar41Weekly Planes
Duration3h 47mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Girardeau to Destin.ExpandLaunch map view
  • Distance: 755.4 mi
  • Duration: 5h 59m

What companies run services between Cape Girardeau, MO, USA and Destin, FL, USA?

Corporate Flight Management Inc, American Airlines, and Allegiant Air fly from Cape Girardeau Municipal Airport (CGI) to Destin–Fort Walton Beach Airport (VPS) once daily.

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