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How to get fromCape Girardeau to Detroitby taxi, train, bus (Greyhound), car, plane, bus, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Cape Girardeau to Detroit by taxi, train, bus (Greyhound), car, plane, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, train

    best
    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Detroittrain train
    12h 50m
    $253–472

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Detroit Bus Stationbus bus
    14h 24m
    $99–193

  3. Drive  580 mi

    1. Drive from Cape Girardeau to Detroitcar car 580 mi
    10h 2m
    $106–153

  4. Taxi to Williamson County Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Detroit (DTW)plane plane MWA - DTW
    7h 57m
    $230–759

  5. Bus, train

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the train from St. Louis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Detroittrain train
    14h 9m
    $164–383

  6. Bus via Auburn Gresham

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Chicagobus bus
    3. Take the bus from Chicago to Detroit Bus Stationbus bus
    16h 34m
    $119–198

  7. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Detroit (DTW)plane plane STL - DTW
    6h 25m
    $629–998

  8. Bus to Memphis, fly

    1. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Detroit (DTW)plane plane MEM - DTW
    8h 41m
    $147–716

Williamson County Regional Airport (MWA) to Detroit (DTW) flights

Calendar28Weekly Planes
Duration7h 55mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Detroit.ExpandLaunch map view
  • Distance: 635.1 mi
  • Duration: 12h 50m

What companies run services between Cape Girardeau, MO, USA and Detroit, MI, USA?

You can take a vehicle from Cape Girardeau to Detroit Bus Station via Cape Girardeau, St Louis Bus Station, and Indianapolis Union Station in around 14h 24m.

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