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How to get fromCape Girardeau to Floridaby plane, bus (Greyhound, Flixbus), car, bus, or taxi

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There are 9 ways to get from Cape Girardeau to Florida by plane, bus (Greyhound, Flixbus), car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cape Girardeau Municipal Airport to Orlando Sanford

    best
    1. Fly from Cape Girardeau Municipal Airport (CGI) to Orlando Sanford (SFB)plane plane CGI - SFB
    3h 7m
    $334–903

  2. Bus to Lambert–St. Louis International Airport, fly to Jacksonville

    cheapest
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Jacksonville (JAX)plane plane STL - JAX
    7h 10m
    $132–599

  3. Bus

    1. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    19h 29m
    $167–278

  4. Drive  754.8 mi

    1. Drive from Cape Girardeau to Jacksonvillecar car 754.8 mi
    13h 54m
    $134–193

  5. Bus to Lambert–St. Louis International Airport, fly to Fort Lauderdale–Hollywood International Airport

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane STL - FLL
    6h 51m
    $143–649

  6. Bus to Lambert–St. Louis International Airport, fly to Tampa

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    7h 2m
    $143–648

  7. Bus to Lambert–St. Louis International Airport, fly to Orlando

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Orlando (MCO)plane plane STL - MCO
    7h 18m
    $215–291

  8. Bus to Lambert–St. Louis International Airport, fly to Ft. Myers

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    8h 21m
    $154–701

  9. Taxi, bus to Nashville, fly to Jacksonville

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Jacksonville (JAX)plane plane BNA - JAX
    9h 37m
    $216–657

Cape Girardeau Municipal Airport (CGI) to Orlando Sanford (SFB) flights

Calendar2Weekly Planes
Duration2h 20mAverage Duration
Ticket$255Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Girardeau to Florida.ExpandLaunch map view
  • Distance: 785.4 mi
  • Duration: 3h 7m

What companies run services between Cape Girardeau, MO, USA and Florida, USA?

Corporate Flight Management Inc flies from Cape Girardeau Municipal Airport (CGI) to Orlando Sanford (SFB) twice a week. Alternatively, you can take a vehicle from Cape Girardeau to Jacksonville via Cape Girardeau, Memphis Bus Station, and Atlanta Bus Station in around 19h 29m.

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