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How to get fromCape Girardeau to Fort Myersby bus, plane, bus (Greyhound, Flixbus), car, taxi, or train

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There are 9 ways to get from Cape Girardeau to Fort Myers by bus, plane, bus (Greyhound, Flixbus), car, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly to Ft. Myers

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    8h 5m
    $160–701

  2. Fly Cape Girardeau Municipal Airport to Ft. Myers

    cheapest
    1. Fly from Cape Girardeau Municipal Airport (CGI) to Ft. Myers (RSW)plane plane CGI - RSW
    7h 52m
    $147–583

  3. Bus

    1. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    25h 24m
    $185–343

  4. Drive 1,001.5 mi

    1. Drive from Cape Girardeau to Fort Myerscar car 1,001.5 mi
    17h 43m
    $183–264

  5. Bus to Lambert–St. Louis International Airport, fly to Sarasota–Bradenton International Airport, bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Sarasota–Bradenton International Airport (SRQ)plane plane STL - SRQ
    3. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    9h 31m
    $190–869

  6. Bus to Midamerica St. Louis Airport, fly to Punta Gorda Airport, taxi

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Midamerica St. Louis Airport (BLV) to Punta Gorda Airport (PGD)plane plane BLV - PGD
    3. Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi taxi
    7h 1m
    $220–599

  7. Taxi, bus to Nashville, fly to Ft. Myers

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Ft. Myers (RSW)plane plane BNA - RSW
    10h 32m
    $233–684

  8. Bus to Lambert–St. Louis International Airport, fly to Tampa, bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    11h 6m
    $470–2,088

  9. Bus, train

    1. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    3. Take the bus from Gulfport to Fort Myersbus bus
    30h 55m
    $238–373

Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) flights

Calendar62Weekly Planes
Duration3h 58mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Fort Myers.ExpandLaunch map view
  • Distance: 1,124.7 mi
  • Duration: 8h 5m

What companies run services between Cape Girardeau, MO, USA and Fort Myers, FL, USA?

You can take a vehicle from Cape Girardeau to Fort Myers Bus Stop via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, and Tampa Bus Station in around 25h 24m. Alternatively, Corporate Flight Management Inc, American Airlines, and two other airlines fly from Cape Girardeau Municipal Airport (CGI) to Ft. Myers (RSW) twice daily.

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