There are 8 ways to get from Cape Girardeau to Fort Wayne by taxi, train, bus, car, plane, bus (Greyhound), or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, train, bus
best- Take the taxi from Cape Girardeau to Carbondaletaxi
- Take the train from Carbondale to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Fort Waynebus
10h 41m$234–369Drive 427.7 mi
cheapest- Drive from Cape Girardeau to Fort Waynecar 427.7 mi
7h 18m$76–110Taxi to Williamson County Regional Airport, fly
- Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi
- Fly from Williamson County Regional Airport (MWA) to Fort Wayne International Airport (FWA)plane MWA - FWA
8h 30m$223–552Bus
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Fort Waynebus
11h 37m$87–165Bus, train
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the train from St. Louis to Chicago Union Stationtrain
- Take the bus from Chicago to Fort Waynebus
13h 55m$196–340Bus via Chicago
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago to Fort Waynebus
14h 55m$96–180Taxi to Barkley Regional Airport, fly
- Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi
- Fly from Barkley Regional Airport (PAH) to Fort Wayne International Airport (FWA)plane PAH - FWA
6h 16m$238–574Fly from Cape Girardeau Municipal Airport
- Fly from Cape Girardeau Municipal Airport (CGI) to Fort Wayne International Airport (FWA)plane CGI - FWA
6h 8m$169–623
Williamson County Regional Airport (MWA) to Fort Wayne International Airport (FWA) flights
Comparing Your Travel Options
The cheapest way to get from Cape Girardeau to Fort Wayne is to drive which costs $75 - $110 and takes 7h 18m.
The fastest way to get from Cape Girardeau to Fort Wayne is to fly which takes 6h 8m and costs $160 - $650.
No, there is no direct bus from Cape Girardeau to Fort Wayne. However, there are services departing from Cape Girardeau and arriving at Coldwater at Northeast via St Louis Bus Station, Indianapolis and Central Station - Bay A. The journey, including transfers, takes approximately 11h 37m.
The distance between Cape Girardeau and Fort Wayne is 475 miles. The road distance is 430.2 miles.
The best way to get from Cape Girardeau to Fort Wayne without a car is to taxi and train and bus which takes 10h 41m and costs $230 - $370.
It takes approximately 10h 41m to get from Cape Girardeau to Fort Wayne, including transfers.
Cape Girardeau to Fort Wayne bus services, operated by Greyhound USA, depart from Cape Girardeau station.
The best way to get from Cape Girardeau to Fort Wayne is to bus which takes 11h 37m and costs $85 - $170. Alternatively, you can fly, which costs $160 - $650 and takes 6h 8m.
Cape Girardeau to Fort Wayne bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Fort Wayne is 1h ahead of Cape Girardeau. It is currently 10:41 AM in Cape Girardeau and 11:41 AM in Fort Wayne.
What companies run services between Cape Girardeau, MO, USA and Fort Wayne, IN, USA?
You can take a vehicle from Cape Girardeau to Coldwater at Northeast via Cape Girardeau, St Louis Bus Station, Indianapolis, Fort Wayne, and Central Station - Bay A in around 11h 37m. Alternatively, Corporate Flight Management Inc, United Airlines, and two other airlines fly from Cape Girardeau Municipal Airport (CGI) to Fort Wayne International Airport (FWA) 3 times a day.
- Website
- aa.com
Flights from Williamson County Regional Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 10h 6m
- When
- Every day
- Estimated price
- $55–350
Flights from Cape Girardeau Municipal Airport to Fort Wayne International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 10m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Cape Girardeau Municipal Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 7h 57m
- When
- Every day
- Estimated price
- $180–600
- Website
- united.com
Flights from Barkley Regional Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $60–360
Flights from Cape Girardeau Municipal Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $180–600
- Website
- allegiantair.com
Flights from Cape Girardeau Municipal Airport to Fort Wayne International Airport via Orlando Sanford
- Ave. Duration
- 6h 19m
- When
- Saturday
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Carbondale to Champaign-Urbana
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $95–160
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Champaign Intermodal Trans Ctr to Indianapolis Union Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Indianapolis to Fort Wayne
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $12–50
- Website
- Barons Bus
Bus from Indianapolis to Fort Wayne
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $12–50
- Website
- Barons Bus
Bus from Chicago to Fort Wayne
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Estimated price
- $16–55
- Website
- Barons Bus
Bus from Chicago to Fort Wayne
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Estimated price
- $16–55
- Website
- Barons Bus
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Schedules at
- Flixbus USA
- Ave. Duration
- 1h 13m
- Estimated price
- $100–170
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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Booking & Getting There
Yes, the driving distance between Cape Girardeau to Fort Wayne is 430 miles. It takes approximately 7h 18m to drive from Cape Girardeau to Fort Wayne.
Book your Cape Girardeau to Fort Wayne bus tickets online with Omio.
There are 88+ hotels available in Fort Wayne.










