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How to get fromCape Girardeau to Gainesvilleby taxi, bus, car, plane, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Cape Girardeau to Gainesville by taxi, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus

    best
    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    15h 30m
    $223–332

  2. Bus to Lambert–St. Louis International Airport, fly to Gainesville Regional Airport

    cheapest
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Gainesville Regional Airport (GNV)plane plane STL - GNV
    9h 21m
    $130–598

  3. Drive 775.3 mi

    1. Drive from Cape Girardeau to Gainesvillecar car 775.3 mi
    13h 21m
    $142–205

  4. Bus

    1. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    17h 54m
    $145–273

  5. Bus to Lambert–St. Louis International Airport, fly to Jacksonville, bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Jacksonville (JAX)plane plane STL - JAX
    3. Take the bus from Jacksonville to Gainesvillebus bus
    9h 40m
    $150–668

  6. Fly Cape Girardeau Municipal Airport to Gainesville Regional Airport

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Gainesville Regional Airport (GNV)plane plane CGI - GNV
    7h 45m
    $136–530

  7. Bus to Midamerica St. Louis Airport, fly to Orlando Sanford, drive

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Midamerica St. Louis Airport (BLV) to Orlando Sanford (SFB)plane plane BLV - SFB
    3. Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar car
    8h 38m
    $156–514

Lambert–St. Louis International Airport (STL) to Gainesville Regional Airport (GNV) flights

Calendar56Weekly Planes
Duration5h 17mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Gainesville.ExpandLaunch map view
  • Distance: 825.8 mi
  • Duration: 15h 30m

What companies run services between Cape Girardeau, MO, USA and Gainesville, FL, USA?

You can take a vehicle from Cape Girardeau to Gainesville via Cape Girardeau, Memphis Bus Station, and Atlanta Bus Station in around 17h 54m. Alternatively, Corporate Flight Management Inc, American Airlines, and Delta fly from Cape Girardeau Municipal Airport (CGI) to Gainesville Regional Airport (GNV) twice daily.

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