There are 9 ways to get from Cape Girardeau to Gatlinburg by taxi, plane, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Williamson County Regional Airport, fly, taxi
best- Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi
- Fly from Williamson County Regional Airport (MWA) to Mcghee Tyson Airport (TYS)plane MWA - TYS
- Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi
7h 12m$463–1,217Drive 411 mi
cheapest- Drive from Cape Girardeau to Gatlinburgcar 411 mi
7h 39m$75–109Taxi, bus, drive
- Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi
- Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Asheville, NCbus
- Drive from Asheville, NC to Gatlinburgcar
21h 53m$254–403Taxi to Barkley Regional Airport, fly, taxi
- Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi
- Fly from Barkley Regional Airport (PAH) to Mcghee Tyson Airport (TYS)plane PAH - TYS
- Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi
9h 18m$453–1,129Bus to Lambert–St. Louis International Airport, fly, taxi
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane STL - TYS
- Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi
8h 44m$317–1,006Fly from Cape Girardeau Municipal Airport, taxi
- Fly from Cape Girardeau Municipal Airport (CGI) to Mcghee Tyson Airport (TYS)plane CGI - TYS
- Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi
6h 44m$334–988Taxi, bus to Nashville, fly
- Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi
- Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus
- Fly from Nashville (BNA) to Mcghee Tyson Airport (TYS)plane BNA - TYS
- Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi
8h 37m$385–989Bus, drive (Greyhound)
- Take the bus from Cape Girardeau to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Asheville, NCbus
- Drive from Asheville, NC to Gatlinburgcar
24h 42m$170–334Bus, train, drive
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
- Take the train from Indianapolis to Ashland Amtrak Stationtrain
- Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Asheville, NCbus
- Drive from Asheville, NC to Gatlinburgcar
28h 22m$225–444
Williamson County Regional Airport (MWA) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Cape Girardeau to Gatlinburg is to drive which costs $75 - $110 and takes 7h 39m.
The fastest way to get from Cape Girardeau to Gatlinburg is to fly and taxi which takes 6h 44m and costs $330 - $1,000.
The distance between Cape Girardeau and Gatlinburg is 408 miles. The road distance is 413.4 miles.
It takes approximately 7h 12m to get from Cape Girardeau to Gatlinburg, including transfers.
Gatlinburg is 1h ahead of Cape Girardeau. It is currently 8:00 PM in Cape Girardeau and 9:00 PM in Gatlinburg.
Yes, the driving distance between Cape Girardeau to Gatlinburg is 413 miles. It takes approximately 7h 39m to drive from Cape Girardeau to Gatlinburg.
There are 7076+ hotels available in Gatlinburg.
What companies run services between Cape Girardeau, MO, USA and Gatlinburg, TN, USA?
There is no direct connection from Cape Girardeau to Gatlinburg. However, you can take the taxi to Williamson County Regional Airport (MWA) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Gatlinburg. Alternatively, you can take the taxi to Carbondale Intermodal Station, take the bus to Atlanta Bus Station, take the bus to Winston Salem(Trans Center), take the bus to Asheville, NC, then drive to Gatlinburg.
- Website
- aa.com
Flights from Williamson County Regional Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 7h 42m
- When
- Every day
- Estimated price
- $160–850
Flights from Lambert–St. Louis International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $180–900
Flights from Lambert–St. Louis International Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $170–900
Flights from Cape Girardeau Municipal Airport to Mcghee Tyson Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 23m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $200–900
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $160–850
Flights from Lambert–St. Louis International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 5h 9m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,000
Flights from Cape Girardeau Municipal Airport to Mcghee Tyson Airport via Pensacola, Atlanta
- Ave. Duration
- 7h 34m
- When
- Wednesday
- Estimated price
- $410–1,500
- Website
- united.com
Flights from Williamson County Regional Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $160–850
Flights from Barkley Regional Airport to Mcghee Tyson Airport via Houston
- Ave. Duration
- 6h 40m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $210–950
Flights from Barkley Regional Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 9h 7m
- When
- Every day
- Estimated price
- $140–750
Flights from Lambert–St. Louis International Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $170–900
Flights from Cape Girardeau Municipal Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $140–750
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $120–750
Flights from Nashville to Mcghee Tyson Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- $80–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Ashland Amtrak Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $85–180
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Carbondale Intermodal Station to Atlanta Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Bus from Carbondale Intermodal Station to Nashville Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $45–95
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Asheville, NC
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Cape Girardeau to Memphis Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $27–55
- Website
- Greyhound
Bus from Memphis Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- 4 times a day
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Atlanta Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $45–95
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Asheville, NC
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- Every 4 hours
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Ashland Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 7h 5m
- Frequency
- Twice daily
- Estimated price
- $45–85
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Asheville, NC
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
- Ave. Duration
- 1h 9m
- Estimated price
- $100–210
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Knoxville Taxi Service
- Phone
- +1 865 691 1900
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Knoxville Taxi Service
- Phone
- +1 865 691 1900
Knoxville Taxi Service
- Phone
- +1 865 691 1900
Knoxville Taxi Service
- Phone
- +1 865 691 1900
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Knoxville Taxi Service
- Phone
- +1 865 691 1900
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide






