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How to get fromCape Girardeau to Greenvilleby taxi, plane, bus, car, or bus (Greyhound)

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There are 7 ways to get from Cape Girardeau to Greenville by taxi, plane, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Williamson County Regional Airport, fly

    best
    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Greenville–Spartanburg International Airport (GSP)plane plane MWA - GSP
    7h 48m
    $318–952

  2. Drive 543.3 mi

    cheapest
    1. Drive from Cape Girardeau to Greenvillecar car 543.3 mi
    9h 47m
    $100–144

  3. Taxi, bus

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    14h 22m
    $231–414

  4. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP)plane plane STL - GSP
    7h 5m
    $172–791

  5. Taxi, bus to Nashville, fly

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Greenville–Spartanburg International Airport (GSP)plane plane BNA - GSP
    8h 2m
    $245–774

  6. Fly from Cape Girardeau Municipal Airport

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Greenville–Spartanburg International Airport (GSP)plane plane CGI - GSP
    6h 18m
    $189–723

  7. Bus

    1. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    17h 27m
    $154–348

Williamson County Regional Airport (MWA) to Greenville–Spartanburg International Airport (GSP) flights

Calendar33Weekly Planes
Duration8h 8mAverage Duration
Ticket$149Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Greenville.ExpandLaunch map view
  • Distance: 496.3 mi
  • Duration: 7h 48m

What companies run services between Cape Girardeau, MO, USA and Greenville, SC, USA?

Corporate Flight Management Inc, American Airlines, and three other airlines fly from Cape Girardeau Municipal Airport (CGI) to Greenville–Spartanburg International Airport (GSP) twice daily. Alternatively, you can take a vehicle from Cape Girardeau to Greenville via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 17h 27m.

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