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How to get fromCape Girardeau to Independenceby bus, train, bus (Greyhound), car, plane, or taxi

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There are 6 ways to get from Cape Girardeau to Independence by bus, train, bus (Greyhound), car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the train from St. Louis to Independence Stationtrain train Missouri River Runner / ...
    8h 4m
    $127–238

  2. Drive 338.8 mi

    cheapest
    1. Drive from Cape Girardeau to Independencecar car 338.8 mi
    5h 46m
    $62–90

  3. Bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US0180s / ...
    8h 37m
    $102–148

  4. Bus to Lambert–St. Louis International Airport, fly, line 24 bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Kansas City (MCI)plane plane STL - MCI
    3. Take the bus from East Village - Bay A to On White Oak At Osage Ebbus bus
    8h 1m
    $135–661

  5. Taxi to Barkley Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Kansas City (MCI)plane plane PAH - MCI
    10h 13m
    $263–819

  6. Taxi to Williamson County Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Kansas City (MCI)plane plane MWA - MCI
    9h 5m
    $263–857

Lambert–St. Louis International Airport (STL) to Kansas City (MCI) flights

Calendar20Weekly Planes
Duration1h 5mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Independence.ExpandLaunch map view
  • Distance: 384.4 mi
  • Duration: 8h 4m

What companies run services between Cape Girardeau, MO, USA and Independence, MO, USA?

You can take a vehicle from Cape Girardeau to On White Oak At Osage Eb via Cape Girardeau, St Louis Bus Station, Kansas City Bus Station, and East Village - Bay A in around 8h 37m.

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