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How to get fromCape Girardeau to Indianaby taxi, train, bus, car, plane, or bus (Greyhound)

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There are 6 ways to get from Cape Girardeau to Indiana by taxi, train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, train, bus

    best
    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    6h 55m
    $166–267

  2. Drive  303.8 mi

    cheapest
    1. Drive from Cape Girardeau to Indianapoliscar car 303.8 mi
    5h 12m
    $56–81

  3. Taxi to Williamson County Regional Airport, fly to Chicago O'Hare International Airport, train

    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)plane plane MWA - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h
    $222–391

  4. Bus (Greyhound)

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    7h 39m
    $59–113

  5. Taxi to Barkley Regional Airport, fly to Chicago O'Hare International Airport, train

    1. Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Chicago O'Hare International Airport (ORD)plane plane PAH - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 12m
    $192–453

  6. Bus to Lambert–St. Louis International Airport, fly to Chicago Midway International Airport, train

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 40m
    $86–410

Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD) flights

Calendar14Weekly Planes
Duration1h 44mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Indiana.ExpandLaunch map view
  • Distance: 346.1 mi
  • Duration: 6h 55m

What companies run services between Cape Girardeau, MO, USA and Indiana, USA?

You can take a vehicle from Cape Girardeau to Indianapolis Union Station via Cape Girardeau and St Louis Bus Station in around 7h 39m.

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Train operators
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