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How to get fromCape Girardeau to Indianapolisby taxi, train, bus, car, plane, or bus (Greyhound)

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There are 7 ways to get from Cape Girardeau to Indianapolis by taxi, train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, train, bus

    best
    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    6h 50m
    $225–317

  2. Drive  303.8 mi

    cheapest
    1. Drive from Cape Girardeau to Indianapoliscar car 303.8 mi
    5h 12m
    $54–78

  3. Taxi to Barkley Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Indianapolis (IND)plane plane PAH - IND
    8h 50m
    $235–721

  4. Bus (Greyhound)

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    7h 39m
    $73–113

  5. Taxi to Williamson County Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Indianapolis (IND)plane plane MWA - IND
    6h 25m
    $220–709

  6. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Indianapolis (IND)plane plane STL - IND
    7h 48m
    $128–648

  7. Fly from Cape Girardeau Municipal Airport

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Indianapolis (IND)plane plane CGI - IND
    5h 33m
    $176–780

Barkley Regional Airport (PAH) to Indianapolis (IND) flights

Calendar28Weekly Planes
Duration8h 8mAverage Duration
Ticket$90Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Girardeau to Indianapolis.ExpandLaunch map view
  • Distance: 346.1 mi
  • Duration: 6h 50m

What companies run services between Cape Girardeau, MO, USA and Indianapolis, IN, USA?

You can take a vehicle from Cape Girardeau to Indianapolis Union Station via Cape Girardeau and St Louis Bus Station in around 7h 39m. Alternatively, Corporate Flight Management Inc and American Airlines fly from Cape Girardeau Municipal Airport (CGI) to Indianapolis (IND) twice daily.

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