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How to get fromCape Girardeau to Indianapolisby taxi, train, bus, car, plane, or bus (Greyhound)

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There are 6 ways to get from Cape Girardeau to Indianapolis by taxi, train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, train, bus

    best
    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Champaign-Urbanatrain train
    3. Take the bus from Champaign to Indianapolisbus bus
    6h 50m

  2. Drive 303.8 mi

    cheapest
    1. Drive from Cape Girardeau to Indianapoliscar car 303.8 mi
    5h 12m
    $56–81

  3. Taxi to Williamson County Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Indianapolis (IND)plane plane MWA - IND
    6h 53m
    $230–709

  4. Bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    7h 19m
    $60–118

  5. Taxi to Barkley Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Indianapolis (IND)plane plane PAH - IND
    7h 32m
    $235–661

  6. Fly from Cape Girardeau Municipal Airport

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Indianapolis (IND)plane plane CGI - IND
    5h 30m
    $186–780

Williamson County Regional Airport (MWA) to Indianapolis (IND) flights

Calendar26Weekly Planes
Duration6h 32mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Indianapolis.ExpandLaunch map view
  • Distance: 346.1 mi
  • Duration: 6h 50m

What companies run services between Cape Girardeau, MO, USA and Indianapolis, IN, USA?

You can take a vehicle from Cape Girardeau to Indianapolis Union Station via Cape Girardeau and St Louis Bus Station in around 7h 19m. Alternatively, Corporate Flight Management Inc, United Airlines, and American Airlines fly from Cape Girardeau Municipal Airport (CGI) to Indianapolis (IND) 4 times a day.

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