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How to get fromCape Girardeau to Iowaby bus, plane, bus (Greyhound), train, car, or bus (Greyhound, Flixbus, Amtrak)

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There are 9 ways to get from Cape Girardeau to Iowa by bus, plane, bus (Greyhound), train, car, or bus (Greyhound, Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly to Omaha

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Omaha (OMA)plane plane STL - OMA
    5h 8m
    $655–971

  2. Drive  430.3 mi

    cheapest
    1. Drive from Cape Girardeau to Des Moinescar car 430.3 mi
    8h 16m
    $79–114

  3. Bus via Kansas City

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    3. Take the bus from Kansas City to Des Moinesbus bus
    11h 19m
    $117–178

  4. Bus, train

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the train from St. Louis to Kansas Citytrain train
    3. Take the bus from Kansas City to Des Moinesbus bus
    13h 45m
    $227–353

  5. Fly Cape Girardeau Municipal Airport to The Eastern Iowa Airport

    1. Fly from Cape Girardeau Municipal Airport (CGI) to The Eastern Iowa Airport (CID)plane plane CGI - CID
    5h 3m
    $164–568

  6. Fly Cape Girardeau Municipal Airport to Des Moines

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Des Moines (DSM)plane plane CGI - DSM
    4h 58m
    $142–531

  7. Fly Cape Girardeau Municipal Airport to Quad City International Airport

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Quad City International Airport (MLI)plane plane CGI - MLI
    5h 59m
    $126–520

  8. Fly Cape Girardeau Municipal Airport to Chicago O'Hare International Airport, bus

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD)plane plane CGI - ORD
    2. Take the bus from Chicago Bus Station to Davenportbus bus
    8h 43m
    $154–446

  9. Bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Springfield SMTD Transfer Centerbus bus
    3. Take the bus from Springfield to Galesburg Amtrak Stationbus bus
    4. Take the bus from Galesburg to Des Moinesbus bus
    14h 30m

Lambert–St. Louis International Airport (STL) to Omaha (OMA) flights

Calendar15Weekly Planes
Duration1h 16mAverage Duration
Ticket$76Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Girardeau to Iowa.ExpandLaunch map view
  • Distance: 479.8 mi
  • Duration: 5h 8m

What companies run services between Cape Girardeau, MO, USA and Iowa, USA?

You can take a vehicle from Cape Girardeau to Des Moines via Cape Girardeau, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 11h 19m. Alternatively, Corporate Flight Management Inc, United Airlines, and two other airlines fly from Cape Girardeau Municipal Airport (CGI) to The Eastern Iowa Airport (CID) 4 times a day.

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