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How to get fromCape Girardeau to Key West (Island)by bus, plane, taxi, car, bus (Greyhound, Flixbus), train, or ferry

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There are 10 ways to get from Cape Girardeau to Key West (Island) by bus, plane, taxi, car, bus (Greyhound, Flixbus), train, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane plane STL - EYW
    8h 3m
    $137–546

  2. Fly from Cape Girardeau Municipal Airport

    cheapest
    1. Fly from Cape Girardeau Municipal Airport (CGI) to Key West International Airport (EYW)plane plane CGI - EYW
    24h 11m
    $109–428

  3. Taxi, bus

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Key West Airportbus bus
    29h 5m
    $296–497

  4. Drive 1,245.5 mi

    1. Drive from Cape Girardeau to Key Westcar car 1,245.5 mi
    22h 28m
    $228–329

  5. Bus to Midamerica St. Louis Airport, fly

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Midamerica St. Louis Airport (BLV) to Key West International Airport (EYW)plane plane BLV - EYW
    16h 21m
    $130–454

  6. Bus to Memphis, fly

    1. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Key West International Airport (EYW)plane plane MEM - EYW
    9h 44m
    $135–544

  7. Taxi, bus to Nashville, fly

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Key West International Airport (EYW)plane plane BNA - EYW
    10h 32m
    $215–594

  8. Taxi to Williamson County Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Key West International Airport (EYW)plane plane MWA - EYW
    7h 44m
    $253–707

  9. Bus

    1. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Key West Airportbus bus
    31h 54m
    $212–418

  10. Bus, train, ferry

    1. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    3. Take the bus from Gulfport to Fort Myersbus bus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    36h 21m
    $418–573

Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW) flights

Calendar49Weekly Planes
Duration5h 45mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Key West (Island).ExpandLaunch map view
  • Distance: 1,231.8 mi
  • Duration: 8h 3m

What companies run services between Cape Girardeau, MO, USA and Key West (Island), FL, USA?

Corporate Flight Management Inc, American Airlines, and two other airlines fly from Cape Girardeau Municipal Airport (CGI) to Key West International Airport (EYW) twice daily. Alternatively, you can take a vehicle from Cape Girardeau to Key West Airport via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, and Miami Airport Station in around 31h 54m.

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