There are 6 ways to get from Cape Girardeau to Lawrence by bus (Greyhound), bus, train, car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Cape Girardeau to St Louis Bus Stationbus Greyhound US1173
- Take the bus from St Louis Bus Station to Lawrence Bus Stopbus Greyhound US0180s
9h 24m$75–122Drive 386 mi
cheapest- Drive from Cape Girardeau to Lawrencecar 386 mi
6h 32m$71–102Bus, train
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the train from St. Louis to Kansas Citytrain
- Take the train from Kansas City to Lawrence Amtrak Stationtrain
10h 42m$196–312Bus to Lambert–St. Louis International Airport, fly, train
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Kansas City (MCI)plane STL - MCI
- Take the train from Kansas City to Lawrence Amtrak Stationtrain
9h 4m$749–1,075Taxi to Williamson County Regional Airport, fly, train
- Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi
- Fly from Williamson County Regional Airport (MWA) to Kansas City (MCI)plane MWA - MCI
- Take the train from Kansas City to Lawrence Amtrak Stationtrain
9h 41m$274–892Taxi to Barkley Regional Airport, fly, train
- Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi
- Fly from Barkley Regional Airport (PAH) to Kansas City (MCI)plane PAH - MCI
- Take the train from Kansas City to Lawrence Amtrak Stationtrain
11h 17m$274–804
Lambert–St. Louis International Airport (STL) to Kansas City (MCI) flights
Comparing Your Travel Options
The cheapest way to get from Cape Girardeau to Lawrence is to drive which costs $70 - $110 and takes 6h 32m.
The fastest way to get from Cape Girardeau to Lawrence is to drive which takes 6h 32m and costs $70 - $110.
No, there is no direct bus from Cape Girardeau to Lawrence. However, there are services departing from Cape Girardeau and arriving at Lawrence Bus Stop via St Louis Bus Station. The journey, including transfers, takes approximately 9h 24m.
The distance between Cape Girardeau and Lawrence is 439 miles. The road distance is 388.2 miles.
The best way to get from Cape Girardeau to Lawrence without a car is to bus which takes 9h 24m and costs $75 - $130.
It takes approximately 9h 24m to get from Cape Girardeau to Lawrence, including transfers.
Cape Girardeau to Lawrence bus services, operated by Greyhound USA, depart from Cape Girardeau station.
Cape Girardeau to Lawrence bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Cape Girardeau to Lawrence is 388 miles. It takes approximately 6h 32m to drive from Cape Girardeau to Lawrence.
Book your Cape Girardeau to Lawrence bus tickets online with Omio.
What companies run services between Cape Girardeau, MO, USA and Lawrence, KS, USA?
You can take a vehicle from Cape Girardeau to Lawrence Bus Stop via Cape Girardeau and St Louis Bus Station in around 9h 24m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Kansas City
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $70–500
- Website
- united.com
Flights from Barkley Regional Airport to Kansas City via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $110–600
Flights from Barkley Regional Airport to Kansas City via Houston
- Ave. Duration
- 8h 12m
- When
- Every day
- Estimated price
- $150–750
- Website
- aa.com
Flights from Williamson County Regional Airport to Kansas City via Chicago O'Hare
- Ave. Duration
- 4h 47m
- When
- Monday, Thursday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Kansas City
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $150–240
- Website
- Amtrak
Train from Kansas City to Lawrence Amtrak Station
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Amtrak
Train from Kansas City to Lawrence Amtrak Station
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Amtrak
Train from Kansas City to Lawrence Amtrak Station
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Amtrak
Train from Kansas City to Lawrence Amtrak Station
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from St Louis Bus Station to Lawrence Bus Stop
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $50–85
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
- Ave. Duration
- 1h 20m
- Estimated price
- $130–170
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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Booking & Getting There
There are 46+ hotels available in Lawrence.






