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How to get fromCape Girardeau to Lexingtonby taxi, train, bus, car, plane, or bus (Greyhound)

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There are 6 ways to get from Cape Girardeau to Lexington by taxi, train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, train, bus

    best
    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Champaign-Urbanatrain train
    3. Take the bus from Champaign to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    11h 52m

  2. Drive 325 mi

    cheapest
    1. Drive from Cape Girardeau to Lexingtoncar car 325 mi
    5h 47m
    $60–86

  3. Taxi to Williamson County Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Blue Grass Airport (LEX)plane plane MWA - LEX
    9h 57m
    $295–1,059

  4. Bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    12h 21m

  5. Taxi to Barkley Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Blue Grass Airport (LEX)plane plane PAH - LEX
    11h 10m
    $295–971

  6. Fly from Cape Girardeau Municipal Airport

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Blue Grass Airport (LEX)plane plane CGI - LEX
    9h 12m
    $266–1,130

Williamson County Regional Airport (MWA) to Blue Grass Airport (LEX) flights

Calendar19Weekly Planes
Duration6h 58mAverage Duration
Ticket$168Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Lexington.ExpandLaunch map view
  • Distance: 551.1 mi
  • Duration: 11h 52m

What companies run services between Cape Girardeau, MO, USA and Lexington, KY, USA?

You can take a vehicle from Cape Girardeau to Lexington via Cape Girardeau, St Louis Bus Station, Indianapolis Union Station, and Lexington Bus Stop in around 12h 21m. Alternatively, Corporate Flight Management Inc, United Airlines, and two other airlines fly from Cape Girardeau Municipal Airport (CGI) to Blue Grass Airport (LEX) 3 times a day.

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