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How to get fromCape Girardeau to Lexingtonby taxi, train, bus, car, or plane

Find Transport to Lexington

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There are 6 ways to get from Cape Girardeau to Lexington by taxi, train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, train, bus, drive

    best
    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    14h 14m
    $260–386

  2. Drive  325 mi

    cheapest
    1. Drive from Cape Girardeau to Lexingtoncar car 325 mi
    5h 47m
    $60–86

  3. Taxi to Williamson County Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Blue Grass Airport (LEX)plane plane MWA - LEX
    10h 12m
    $215–609

  4. Bus, drive

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    14h 26m
    $104–234

  5. Taxi to Barkley Regional Airport, fly

    1. Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Blue Grass Airport (LEX)plane plane PAH - LEX
    10h 37m
    $215–561

  6. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane plane STL - LEX
    9h 50m
    $107–473

Williamson County Regional Airport (MWA) to Blue Grass Airport (LEX) flights

Calendar17Weekly Planes
Duration10h 7mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Girardeau to Lexington.ExpandLaunch map view
  • Distance: 548.7 mi
  • Duration: 14h 14m

What companies run services between Cape Girardeau, MO, USA and Lexington, KY, USA?

There is no direct connection from Cape Girardeau to Lexington. However, you can take the taxi to Carbondale, take the train to Champaign-Urbana, walk to Champaign Intermodal Trans Ctr, take the bus to Indianapolis Union Station, take the bus to Louisville, KY, walk to Roy Wilkins @ W Broadway, take the line 93 bus to Chestnut @ 8th, walk to S 5th @ W Jefferson, take the line 31 bus to Middletown Station @ Target, then drive to Lexington. Alternatively, you can drive from Cape Girardeau to Lexington in around 5h 47m.

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