There are 7 ways to get from Cape Girardeau to Macomb by bus, train, taxi, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the train from St. Louis to Springfieldtrain
- Take the bus from Springfield to Galesburg Amtrak Stationbus
- Take the train from Galesburg Amtrak Station to Macomb Stationtrain
9h 28m$117–223Drive 261.5 mi
cheapest- Drive from Cape Girardeau to Macombcar 261.5 mi
5h 23m$48–69Taxi, train
- Take the taxi from Cape Girardeau to Carbondaletaxi
- Take the train from Carbondale to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Macomb Stationtrain
10h 54m$278–502Fly Cape Girardeau Municipal Airport to Burlington Municipal Airport, taxi
- Fly from Cape Girardeau Municipal Airport (CGI) to Burlington Municipal Airport (BRL)plane CGI - BRL
- Take the taxi from Burlington Municipal Airport (BRL) to Macombtaxi
10h 44m$224–508Bus, train via Springfield
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Springfield SMTD Transfer Centerbus
- Take the bus from Springfield to Galesburg Amtrak Stationbus
- Take the train from Galesburg Amtrak Station to Macomb Stationtrain
10h 11m$104–186Taxi to Williamson County Regional Airport, fly to Burlington Municipal Airport, taxi
- Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi
- Fly from Williamson County Regional Airport (MWA) to Burlington Municipal Airport (BRL)plane MWA - BRL
- Take the taxi from Burlington Municipal Airport (BRL) to Macombtaxi
7h 14m$343–667Fly Cape Girardeau Municipal Airport to Chicago O'Hare International Airport, train
- Fly from Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD)plane CGI - ORD
- Take the train from Chicago Union Station to Macomb Stationtrain
7h 20m$201–423
Cape Girardeau Municipal Airport (CGI) to Burlington Municipal Airport (BRL) flights
Questions & Answers
The cheapest way to get from Cape Girardeau to Macomb is to drive which costs $45 - $70 and takes 5h 23m.
The fastest way to get from Cape Girardeau to Macomb is to drive which takes 5h 23m and costs $45 - $70.
The distance between Cape Girardeau and Macomb is 420 miles. The road distance is 263 miles.
The best way to get from Cape Girardeau to Macomb without a car is to bus and train which takes 9h 28m and costs $110 - $230.
It takes approximately 9h 28m to get from Cape Girardeau to Macomb, including transfers.
Yes, the driving distance between Cape Girardeau to Macomb is 263 miles. It takes approximately 5h 23m to drive from Cape Girardeau to Macomb.
There are four+ hotels available in Macomb.
What companies run services between Cape Girardeau, MO, USA and Macomb, IL, USA?
There is no direct connection from Cape Girardeau to Macomb. However, you can take the taxi to Cape Girardeau, take the bus to St Louis Bus Station, walk to St. Louis, take the train to Springfield, walk to Springfield, take the bus to Galesburg Amtrak Station, walk to Galesburg Amtrak Station, then take the train to Macomb Station. Alternatively, you can take the taxi to Carbondale, take the train to Chicago Union Station, then take the train to Macomb Station.
- Website
- contouraviation.com
Flights from Cape Girardeau Municipal Airport to Burlington Municipal Airport via Chicago O'Hare International Airport
- Ave. Duration
- 9h 20m
- When
- Every day
- Estimated price
- $90–340
Flights from Williamson County Regional Airport to Burlington Municipal Airport via Chicago O'Hare International Airport
- Ave. Duration
- 7h 37m
- When
- Every day
- Estimated price
- $100–370
Flights from Cape Girardeau Municipal Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $95–220
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Springfield
- Ave. Duration
- 1h 38m
- Frequency
- 5 times a day
- Estimated price
- $30–65
- Website
- Amtrak
Train from Galesburg Amtrak Station to Macomb Station
- Ave. Duration
- 41 min
- Frequency
- Twice daily
- Estimated price
- $28–60
- Website
- Amtrak
Train from Carbondale to Chicago Union Station
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $95–210
- Website
- Amtrak
Train from Chicago Union Station to Macomb Station
- Ave. Duration
- 3h 24m
- Frequency
- Twice daily
- Estimated price
- $80–170
- Website
- Amtrak
Train from Galesburg Amtrak Station to Macomb Station
- Ave. Duration
- 41 min
- Frequency
- Twice daily
- Estimated price
- $28–60
- Website
- Amtrak
Train from Chicago Union Station to Macomb Station
- Ave. Duration
- 3h 24m
- Frequency
- Twice daily
- Estimated price
- $80–170
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Springfield to Galesburg Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Amtrak
Bus from Springfield to Galesburg Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Springfield SMTD Transfer Center
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $15–26
- Schedules at
- Flixbus USA
- Ave. Duration
- 1h 9m
- Estimated price
- $100–160
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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