Rome2Rio

How to get fromCape Girardeau to Manhattanby bus, plane, bus (Greyhound), taxi, train, or car

Find Transport to Manhattan

See all options

There are 11 ways to get from Cape Girardeau to Manhattan by bus, plane, bus (Greyhound), taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly to Laguardia Airport

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    6h 42m
    $203–594

  2. Fly Cape Girardeau Municipal Airport to Laguardia Airport

    cheapest
    1. Fly from Cape Girardeau Municipal Airport (CGI) to Laguardia Airport (LGA)plane plane CGI - LGA
    6h 34m
    $157–681

  3. Bus (Greyhound)

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus Greyhound US0421
    27h 39m
    $207–318

  4. Taxi, train

    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    4. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    28h 5m
    $783–1,209

  5. Drive  988.1 mi

    1. Drive from Cape Girardeau to Manhattancar car 988.1 mi
    17h 50m
    $181–261

  6. Bus to Lambert–St. Louis International Airport, fly to Newark Liberty International Airport

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Newark Liberty International Airport (EWR)plane plane STL - EWR
    6h 43m
    $242–970

  7. Bus to Lambert–St. Louis International Airport, fly to Philadelphia International Airport, train

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane plane STL - PHL
    3. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    8h 7m
    $172–1,395

  8. Bus to Memphis, fly to Laguardia Airport

    1. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Laguardia Airport (LGA)plane plane MEM - LGA
    9h
    $201–862

  9. Taxi, bus to Nashville, fly to Laguardia Airport

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Laguardia Airport (LGA)plane plane BNA - LGA
    9h 29m
    $258–877

  10. Taxi, bus to Nashville, fly to Newark Liberty International Airport

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Newark Liberty International Airport (EWR)plane plane BNA - EWR
    9h 32m
    $617–1,803

  11. Bus, train

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the train from St. Louis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    29h 1m
    $677–1,128

Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA) flights

Calendar80Weekly Planes
Duration2h 49mAverage Duration
Ticket$136Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Cape Girardeau to Manhattan.ExpandLaunch map view
  • Distance: 1,023.4 mi
  • Duration: 6h 42m

What companies run services between Cape Girardeau, MO, USA and Manhattan, NY, USA?

You can take a vehicle from Cape Girardeau to Port Authority Bus Terminal via Cape Girardeau and St Louis Bus Station in around 27h 39m. Alternatively, Corporate Flight Management Inc, American Airlines, and two other airlines fly from Cape Girardeau Municipal Airport (CGI) to Laguardia Airport (LGA) 4 times a day.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There