Rome2Rio

How to get fromCape Girardeau to Mobileby bus, plane, car, train, or taxi

Find Transport to Mobile

See all options

There are 6 ways to get from Cape Girardeau to Mobile by bus, plane, car, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly to Destin–Fort Walton Beach Airport, drive

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    7h 29m
    $126–507

  2. Bus to Lambert–St. Louis International Airport, fly to Pensacola International Airport, bus

    cheapest
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS)plane plane STL - PNS
    3. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h 54m
    $96–394

  3. Bus, train

    1. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus Greyhound US1173
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train Amtrak Mardi Gras Service / ...
    18h 22m
    $127–238

  4. Taxi, train

    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    18h 36m
    $293–562

  5. Drive  531.6 mi

    1. Drive from Cape Girardeau to Mobilecar car 531.6 mi
    9h 59m
    $97–141

  6. Bus to Midamerica St. Louis Airport, fly to Destin–Fort Walton Beach Airport, drive

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    7h 49m
    $134–475

Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar26Weekly Planes
Duration2h 55mAverage Duration
Ticket$80Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Cape Girardeau to Mobile.ExpandLaunch map view
  • Distance: 845 mi
  • Duration: 7h 29m

What companies run services between Cape Girardeau, MO, USA and Mobile, AL, USA?

There is no direct connection from Cape Girardeau to Mobile. However, you can take the taxi to Cape Girardeau, take the bus to St Louis Bus Station, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Destin–Fort Walton Beach Airport (VPS), then drive to Mobile. Alternatively, you can take a vehicle from Cape Girardeau to Mobile Amtrak Sta via Cape Girardeau, New Orleans Bus Station, and New Orleans Union Passenger Terminal in around 18h 22m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound