There are 8 ways to get from Cape Girardeau to Moline by taxi, train, bus, car, plane, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, train
best- Take the taxi from Cape Girardeau to Carbondaletaxi
- Take the train from Carbondale to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the taxi from Galesburg Amtrak Station to Molinetaxi
11h 8m$358–622Drive 353.3 mi
cheapest- Drive from Cape Girardeau to Molinecar 353.3 mi
6h 30m$65–94Bus, train
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the train from St. Louis to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Moline Center Stationbus
13h 13m$128–282Taxi to Williamson County Regional Airport, fly
- Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi
- Fly from Williamson County Regional Airport (MWA) to Quad City International Airport (MLI)plane MWA - MLI
6h 56m$199–568Taxi, bus
- Take the taxi from Cape Girardeau to Anna - Shelltaxi
- Take the bus from Anna - Shell to Chicagobus
- Take the bus from Chicago Bus Station to Moline Center Stationbus
13h 44m$173–224Bus
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Moline Center Stationbus
14h 14m$98–157Taxi to Barkley Regional Airport, fly
- Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi
- Fly from Barkley Regional Airport (PAH) to Quad City International Airport (MLI)plane PAH - MLI
7h 34m$204–530Fly from Cape Girardeau Municipal Airport
- Fly from Cape Girardeau Municipal Airport (CGI) to Quad City International Airport (MLI)plane CGI - MLI
7h 58m$125–529
Williamson County Regional Airport (MWA) to Quad City International Airport (MLI) flights
Comparing Your Travel Options
The cheapest way to get from Cape Girardeau to Moline is to drive which costs $60 - $95 and takes 6h 30m.
The fastest way to get from Cape Girardeau to Moline is to drive which takes 6h 30m and costs $60 - $95.
No, there is no direct bus from Cape Girardeau to Moline station. However, there are services departing from Cape Girardeau and arriving at Moline Center Station via St Louis Bus Station and Chicago Bus Station. The journey, including transfers, takes approximately 14h 14m.
The distance between Cape Girardeau and Moline is 564 miles. The road distance is 355.4 miles.
The best way to get from Cape Girardeau to Moline without a car is to taxi and train which takes 11h 8m and costs $350 - $650.
It takes approximately 11h 8m to get from Cape Girardeau to Moline, including transfers.
Cape Girardeau to Moline bus services, operated by Greyhound USA, depart from Cape Girardeau station.
The best way to get from Cape Girardeau to Moline is to bus which takes 14h 14m and costs $95 - $160. Alternatively, you can fly, which costs $120 - $550 and takes 7h 58m.
Cape Girardeau to Moline bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Cape Girardeau to Moline is 355 miles. It takes approximately 6h 30m to drive from Cape Girardeau to Moline.
What companies run services between Cape Girardeau, MO, USA and Moline, IL, USA?
You can take a vehicle from Cape Girardeau to Moline Center Station via Cape Girardeau, St Louis Bus Station, and Chicago Bus Station in around 14h 14m. Alternatively, Corporate Flight Management Inc and American Airlines fly from Cape Girardeau Municipal Airport (CGI) to Quad City International Airport (MLI) twice daily.
- Website
- aa.com
Flights from Williamson County Regional Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $65–410
Flights from Williamson County Regional Airport to Quad City International Airport via Chicago O'Hare, Charlotte
- Ave. Duration
- 9h 7m
- When
- Monday, Thursday, Friday, Saturday, Sunday, and Wednesday
- Estimated price
- $140–700
Flights from Williamson County Regional Airport to Quad City International Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 10h 4m
- When
- Every day
- Estimated price
- $160–750
Flights from Cape Girardeau Municipal Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 6h 53m
- When
- Every day
- Estimated price
- $140–600
Flights from Cape Girardeau Municipal Airport to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 52m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $100–500
Flights from Cape Girardeau Municipal Airport to Quad City International Airport via Dallas/Ft.Worth, Chicago O'Hare
- Ave. Duration
- 8h 46m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
- Website
- united.com
Flights from Barkley Regional Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $60–360
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Carbondale to Chicago Union Station
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $85–220
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $40–120
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $75–200
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Chicago Bus Station to Moline Center Station
- Ave. Duration
- 4h 15m
- Frequency
- 3 times a day
- Estimated price
- $28–45
- Website
- Greyhound
Bus from Chicago Bus Station to Moline Center Station
- Ave. Duration
- 4h 15m
- Frequency
- 3 times a day
- Estimated price
- $28–45
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Chicago Bus Station to Moline Center Station
- Ave. Duration
- 4h 15m
- Frequency
- 3 times a day
- Estimated price
- $28–45
- Website
- Greyhound
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Anna - Shell to Chicago
- Ave. Duration
- 6h 20m
- Frequency
- Once daily
- Estimated price
- $70–90
- Schedules at
- Tornado Bus Company
- Adult
- $70–90
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
- Ave. Duration
- 1h 5m
- Estimated price
- $70–170
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
United American Cab Co
- Phone
- +1-309-341-6161
- Website
- galesburgtaxi.com
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
Book your Cape Girardeau to Moline bus tickets online with Omio.
There are 95+ hotels available in Moline.








