There are 8 ways to get from Cape Girardeau to Naples by bus, plane, taxi, car, bus (Greyhound, Flixbus), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Lambert–St. Louis International Airport, fly to Miami International Airport, bus
best- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA)plane STL - MIA
- Take the bus from Miami Airport to Naples, FLbus
9h 33m$629–1,088Bus to Lambert–St. Louis International Airport, fly to Ft. Myers
cheapest- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane STL - RSW
11h 53m$161–704Taxi, bus
- Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi
- Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to University of South Floridabus
- Take the bus from University of South Florida - 3801 USF Holly Dr to Naples, FLbus
22h 31m$305–474Drive 1,035.2 mi
- Drive from Cape Girardeau to Naplescar 1,035.2 mi
18h 20m$189–273Bus to Lambert–St. Louis International Airport, fly to Sarasota–Bradenton International Airport, bus
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Sarasota–Bradenton International Airport (SRQ)plane STL - SRQ
- Take the bus from Bradenton/Sarasota - Mobil Gas Station to Naples, FLbus
10h 37m$228–932Taxi, bus to Nashville, fly to Sarasota–Bradenton International Airport, bus
- Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi
- Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus
- Fly from Nashville (BNA) to Sarasota–Bradenton International Airport (SRQ)plane BNA - SRQ
- Take the bus from Bradenton/Sarasota - Mobil Gas Station to Naples, FLbus
13h 4m$296–915Bus
- Take the bus from Cape Girardeau to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to University of South Floridabus
- Take the bus from University of South Florida - 3801 USF Holly Dr to Naples, FLbus
25h 20m$221–405Bus, train
- Take the bus from Cape Girardeau to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
- Take the bus from Gulfport to Fort Myersbus
34h 19m$284–441
Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA) flights
Questions & Answers
The cheapest way to get from Cape Girardeau to Naples is to drive which costs $180 - $280 and takes 18h 20m.
The fastest way to get from Cape Girardeau to Naples is to bus and fly which takes 9h 33m and costs $600 - $1,100.
No, there is no direct bus from Cape Girardeau to Naples. However, there are services departing from Cape Girardeau and arriving at Naples, FL via Memphis Bus Station, Atlanta Bus Station and University of South Florida - 3801 USF Holly Dr. The journey, including transfers, takes approximately 25h 20m.
The distance between Cape Girardeau and Naples is 1341 miles. The road distance is 1041.3 miles.
The best way to get from Cape Girardeau to Naples without a car is to taxi and bus which takes 22h 31m and costs $300 - $480.
It takes approximately 9h 33m to get from Cape Girardeau to Naples, including transfers.
Cape Girardeau to Naples bus services, operated by Greyhound USA, depart from Cape Girardeau station.
Cape Girardeau to Naples bus services, operated by Greyhound USA, arrive at Memphis Bus Station.
Naples is 1h ahead of Cape Girardeau. It is currently 5:40 PM in Cape Girardeau and 6:40 PM in Naples.
Yes, the driving distance between Cape Girardeau to Naples is 1041 miles. It takes approximately 18h 20m to drive from Cape Girardeau to Naples.
What companies run services between Cape Girardeau, MO, USA and Naples, FL, USA?
You can take a vehicle from Cape Girardeau to Naples via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, University of South Florida - 3801 USF Holly Dr, and Naples, FL in around 25h 20m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Miami International Airport
- Ave. Duration
- 2h 41m
- When
- Every day
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Miami International Airport via Nashville
- Ave. Duration
- 6h 5m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Sarasota–Bradenton International Airport
- Ave. Duration
- 2h 20m
- When
- Saturday
- Estimated price
- $150–800
Flights from Lambert–St. Louis International Airport to Sarasota–Bradenton International Airport via Nashville
- Ave. Duration
- 4h 25m
- When
- Tuesday to Friday
- Estimated price
- $160–800
Flights from Lambert–St. Louis International Airport to Sarasota–Bradenton International Airport via Orlando
- Ave. Duration
- 4h 33m
- When
- Tuesday to Friday
- Estimated price
- $160–800
Flights from Lambert–St. Louis International Airport to Sarasota–Bradenton International Airport via Chicago Midway
- Ave. Duration
- 5h 5m
- When
- Saturday, Sunday, Tuesday, and Wednesday
- Estimated price
- $200–900
Flights from Lambert–St. Louis International Airport to Ft. Myers
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- $130–650
Flights from Lambert–St. Louis International Airport to Ft. Myers via Nashville
- Ave. Duration
- 4h 5m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $130–650
Flights from Lambert–St. Louis International Airport to Ft. Myers via Orlando
- Ave. Duration
- 4h 56m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Nashville to Sarasota–Bradenton International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $110–650
Flights from Nashville to Sarasota–Bradenton International Airport via Orlando
- Ave. Duration
- 4h 20m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $120–650
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Sarasota–Bradenton International Airport via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $160–800
Flights from Lambert–St. Louis International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $130–650
Flights from Nashville to Sarasota–Bradenton International Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $110–650
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Miami International Airport
- Ave. Duration
- 2h 53m
- When
- Every day
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Ft. Myers via Charlotte
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $150–700
Flights from Nashville to Sarasota–Bradenton International Airport via Charlotte
- Ave. Duration
- 4h 33m
- When
- Sunday
- Estimated price
- $140–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $21–45
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Cape Girardeau to Memphis Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $27–55
- Website
- Greyhound
Bus from Memphis Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- 4 times a day
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Cape Girardeau to New Orleans Bus Station
- Ave. Duration
- 14h 35m
- Frequency
- Twice daily
- Estimated price
- $85–170
- Website
- Greyhound
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Miami Airport to Naples, FL
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- RedCoach
Bus from University of South Florida - 3801 USF Holly Dr to Naples, FL
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- RedCoach
Bus from Bradenton/Sarasota - Mobil Gas Station to Naples, FL
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- RedCoach
Bus from Bradenton/Sarasota - Mobil Gas Station to Naples, FL
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- RedCoach
Bus from University of South Florida - 3801 USF Holly Dr to Naples, FL
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- RedCoach
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Carbondale Intermodal Station to Atlanta Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to University of South Florida
- Ave. Duration
- 7h 55m
- Frequency
- Twice daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Bus from Carbondale Intermodal Station to Nashville Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to University of South Florida
- Ave. Duration
- 7h 55m
- Frequency
- Twice daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Gulfport to Fort Myers
- Ave. Duration
- 13h 17m
- Frequency
- Once daily
- Estimated price
- $120–150
- Schedules at
- Omnibus Express
- Ave. Duration
- 1h
- Estimated price
- $100–130
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Cape Girardeau to Naples bus tickets online with Omio.
There are 1471+ hotels available in Naples.












