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How to get fromCape Girardeau to Niagara Fallsby taxi, plane, bus, train, bus (Greyhound), or car

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There are 11 ways to get from Cape Girardeau to Niagara Falls by taxi, plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Williamson County Regional Airport, fly to Buffalo Niagara International Airport, bus

    best
    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Buffalo Niagara International Airport (BUF)plane plane MWA - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    8h 21m
    $278–866

  2. Fly Cape Girardeau Municipal Airport to Toronto Island Airport, bus

    cheapest
    1. Fly from Cape Girardeau Municipal Airport (CGI) to Toronto Island Airport (YTZ)plane plane CGI - YTZ
    2. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    8h 56m
    $101–453

  3. Taxi, train

    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    19h 54m
    $382–832

  4. Bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Columbusbus bus
    3. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    22h 12m
    $126–255

  5. Drive 806.1 mi

    1. Drive from Cape Girardeau to Niagara Fallscar car 806.1 mi
    14h 15m
    $148–213

  6. Taxi to Barkley Regional Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Buffalo Niagara International Airport (BUF)plane plane PAH - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    10h 35m
    $268–828

  7. Fly Cape Girardeau Municipal Airport to Buffalo Niagara International Airport, bus

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Buffalo Niagara International Airport (BUF)plane plane CGI - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    8h 8m
    $149–687

  8. Bus to Lambert–St. Louis International Airport, fly to Toronto Pearson International Airport, bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Toronto Pearson International Airport (YYZ)plane plane STL - YYZ
    3. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    9h 46m
    $120–530

  9. Taxi, bus to Nashville, fly to Buffalo Niagara International Airport, bus

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Buffalo Niagara International Airport (BUF)plane plane BNA - BUF
    4. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    10h 14m
    $260–893

  10. Bus, train

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the train from St. Louis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    21h 13m
    $293–733

  11. Bus via Pittsburgh

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    27h 2m
    $161–415

Williamson County Regional Airport (MWA) to Buffalo Niagara International Airport (BUF) flights

Calendar26Weekly Planes
Duration6h 35mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Niagara Falls.ExpandLaunch map view
  • Distance: 737.4 mi
  • Duration: 8h 21m

What companies run services between Cape Girardeau, MO, USA and Niagara Falls, NY, USA?

You can take a vehicle from Cape Girardeau to Main Street & Pine Avenue via Cape Girardeau, St Louis Bus Station, Columbus - Mound St, and Ellicott Street & MTC Static in around 22h 12m.

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