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How to get fromCape Girardeau to Ohioby bus, plane, bus (Greyhound), taxi, train, or car

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There are 6 ways to get from Cape Girardeau to Ohio by bus, plane, bus (Greyhound), taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Cleveland-Hopkins International Airport

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)plane plane STL - CLE
    5h 44m
    $520–942

  2. Drive  460.5 mi

    cheapest
    1. Drive from Cape Girardeau to Columbuscar car 460.5 mi
    8h 17m
    $84–122

  3. Bus (Greyhound)

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Columbusbus bus Greyhound US0421
    13h 49m
    $89–146

  4. Taxi, train, bus

    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Toledotrain train
    4. Take the bus from Toledo to Columbus - Mound Stbus bus
    15h 19m
    $254–477

  5. Bus, fly to John Glenn Columbus International Airport

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH)plane plane STL - CMH
    6h 2m
    $829–942

  6. Bus, fly to Detroit

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Detroit (DTW)plane plane STL - DTW
    3. Take the bus from Dearborn to Toledobus bus
    8h 26m
    $702–1,024

Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE) flights

Calendar49Weekly Planes
Duration2h 40mAverage Duration
Ticket$89Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Girardeau to Ohio.ExpandLaunch map view
  • Distance: 628.1 mi
  • Duration: 5h 44m

What companies run services between Cape Girardeau, MO, USA and Ohio, USA?

You can take a vehicle from Cape Girardeau to Columbus via Cape Girardeau and St Louis Bus Station in around 13h 49m.

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