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How to get fromCape Girardeau to Ohioby bus, plane, bus (Greyhound), or car

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There are 7 ways to get from Cape Girardeau to Ohio by bus, plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly to Cleveland-Hopkins International Airport

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)plane plane STL - CLE
    5h 44m
    $521–949

  2. Drive 460.5 mi

    cheapest
    1. Drive from Cape Girardeau to Columbuscar car 460.5 mi
    8h 17m
    $84–122

  3. Bus via Indianapolis

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis to Columbusbus bus
    11h 58m

  4. Bus to Lambert–St. Louis International Airport, fly to John Glenn Columbus International Airport

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH)plane plane STL - CMH
    6h 2m
    $830–949

  5. Fly Cape Girardeau Municipal Airport to Dayton

    1. Fly from Cape Girardeau Municipal Airport (CGI) to Dayton (DAY)plane plane CGI - DAY
    7h 27m
    $336–1,430

  6. Bus to Lambert–St. Louis International Airport, fly to Detroit, bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Detroit (DTW)plane plane STL - DTW
    3. Take the bus from Dearborn to Toledobus bus
    8h 31m
    $511–1,042

  7. Bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Columbusbus bus Greyhound US0421
    12h 34m
    $90–173

Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE) flights

Calendar38Weekly Planes
Duration2h 38mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Ohio.ExpandLaunch map view
  • Distance: 628.1 mi
  • Duration: 5h 44m

What companies run services between Cape Girardeau, MO, USA and Ohio, USA?

You can take a vehicle from Cape Girardeau to Columbus via Cape Girardeau, St Louis Bus Station, Indianapolis, Illinois St (Greyhound Bus Station), and Indianapolis in around 11h 58m. Alternatively, Corporate Flight Management Inc, United Airlines, and two other airlines fly from Cape Girardeau Municipal Airport (CGI) to Dayton (DAY) 5 times a day.

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