There are 8 ways to get from Cape Girardeau to Sioux Falls by taxi, plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Williamson County Regional Airport, fly
best- Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi
- Fly from Williamson County Regional Airport (MWA) to Sioux Falls (FSD)plane MWA - FSD
8h 18m$225–629Fly from Cape Girardeau Municipal Airport
cheapest- Fly from Cape Girardeau Municipal Airport (CGI) to Sioux Falls (FSD)plane CGI - FSD
6h 13m$106–440Bus
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Kansas City Bus Stationbus
- Take the bus from Kansas City to Sioux Fallsbus
18h 7m$156–260Taxi, train, bus
- Take the taxi from Cape Girardeau to Carbondaletaxi
- Take the train from Carbondale to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Albert Leabus
- Take the bus from Albert Lea to Sioux Fallsbus
22h 20m$421–739Drive 706.4 mi
- Drive from Cape Girardeau to Sioux Fallscar 706.4 mi
11h 40m$129–187Taxi to Barkley Regional Airport, fly
- Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi
- Fly from Barkley Regional Airport (PAH) to Sioux Falls (FSD)plane PAH - FSD
8h 16m$225–581Bus to Lambert–St. Louis International Airport, fly
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Sioux Falls (FSD)plane STL - FSD
8h 45m$119–528Bus, train
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the train from St. Louis to Kansas Citytrain
- Take the bus from Kansas City to Sioux Fallsbus
20h 33m$211–375
Williamson County Regional Airport (MWA) to Sioux Falls (FSD) flights
Questions & Answers
The cheapest way to get from Cape Girardeau to Sioux Falls is to drive which costs $120 - $190 and takes 11h 40m.
The fastest way to get from Cape Girardeau to Sioux Falls is to fly which takes 6h 13m and costs $100 - $440.
No, there is no direct bus from Cape Girardeau to Sioux Falls. However, there are services departing from Cape Girardeau and arriving at The Bus Stop via St Louis Bus Station, Kansas City and Maple/Career NE corner. The journey, including transfers, takes approximately 18h 7m.
The distance between Cape Girardeau and Sioux Falls is 638 miles. The road distance is 710.5 miles.
The best way to get from Cape Girardeau to Sioux Falls without a car is to bus which takes 18h 7m and costs $150 - $260.
It takes approximately 8h 18m to get from Cape Girardeau to Sioux Falls, including transfers.
Cape Girardeau to Sioux Falls bus services, operated by Greyhound USA, depart from Cape Girardeau station.
The best way to get from Cape Girardeau to Sioux Falls is to bus which takes 18h 7m and costs $150 - $260. Alternatively, you can fly, which costs $100 - $440 and takes 6h 13m.
Cape Girardeau to Sioux Falls bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Cape Girardeau to Sioux Falls is 711 miles. It takes approximately 11h 40m to drive from Cape Girardeau to Sioux Falls.
What companies run services between Cape Girardeau, MO, USA and Sioux Falls, SD, USA?
You can take a vehicle from Cape Girardeau to The Bus Stop via Cape Girardeau, St Louis Bus Station, Kansas City Bus Station, Kansas City, Sioux Falls, and Maple/Career NE corner in around 18h 7m. Alternatively, Corporate Flight Management Inc, United Airlines, and two other airlines fly from Cape Girardeau Municipal Airport (CGI) to Sioux Falls (FSD) 4 times a day.
- Website
- united.com
Flights from Williamson County Regional Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $90–470
Flights from Barkley Regional Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $80–410
Flights from Lambert–St. Louis International Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $95–500
Flights from Lambert–St. Louis International Airport to Sioux Falls via Denver
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $140–650
Flights from Cape Girardeau Municipal Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $80–410
- Website
- aa.com
Flights from Williamson County Regional Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $90–470
Flights from Lambert–St. Louis International Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $95–500
Flights from Lambert–St. Louis International Airport to Sioux Falls via Dallas/Ft.Worth
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $140–650
Flights from Cape Girardeau Municipal Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $80–410
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Sioux Falls via Minneapolis
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $90–480
Flights from Lambert–St. Louis International Airport to Sioux Falls via Atlanta
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $160–700
Flights from Cape Girardeau Municipal Airport to Sioux Falls via Chicago O'Hare, Minneapolis
- Ave. Duration
- 9h 55m
- When
- Every day
- Estimated price
- $220–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Carbondale to Chicago Union Station
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $100–210
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
Train from St. Louis to Kansas City
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Kansas City Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Sioux Falls
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- https://www.jeffersonlines.com
- Adult
- $95–140
Bus from St. Paul to Albert Lea
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a week
- Estimated price
- $30–50
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–50
Bus from Albert Lea to Sioux Falls
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $45–70
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–70
Bus from Kansas City to Sioux Falls
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- https://www.jeffersonlines.com
- Adult
- $95–140
- Ave. Duration
- 1h 13m
- Estimated price
- $100–170
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 80+ hotels available in Sioux Falls.








