There are 5 ways to get from Cape Girardeau to Topeka by bus (Greyhound), bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Cape Girardeau to St Louis Bus Stationbus Greyhound US1173
- Take the bus from St Louis Bus Station to Topekabus Greyhound US1200 / ...
9h 49m$82–123Drive 409.3 mi
cheapest- Drive from Cape Girardeau to Topekacar 409.3 mi
6h 52m$75–108Bus, train
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the train from St. Louis to Kansas Citytrain
- Take the train from Kansas City to Topeka Stationtrain
11h 18m$212–338Fly Cape Girardeau Municipal Airport to Manhattan Regional Airport, drive
- Fly from Cape Girardeau Municipal Airport (CGI) to Manhattan Regional Airport (MHK)plane CGI - MHK
- Drive from Manhattan Regional Airport (MHK) to Topekacar
9h 50m$115–475Bus to Lambert–St. Louis International Airport, fly to Kansas City, bus
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Kansas City (MCI)plane STL - MCI
- Take the bus from 2745 Southwest Blvd - Kansas City to Quincy Street Station - Topekabus
8h 57m$770–1,096
Cape Girardeau Municipal Airport (CGI) to Manhattan Regional Airport (MHK) flights
Comparing Your Travel Options
The cheapest way to get from Cape Girardeau to Topeka is to drive which costs $70 - $110 and takes 6h 52m.
The fastest way to get from Cape Girardeau to Topeka is to drive which takes 6h 52m and costs $70 - $110.
No, there is no direct bus from Cape Girardeau to Topeka. However, there are services departing from Cape Girardeau and arriving at Topeka via St Louis Bus Station. The journey, including transfers, takes approximately 9h 49m.
The distance between Cape Girardeau and Topeka is 429 miles. The road distance is 411.7 miles.
The best way to get from Cape Girardeau to Topeka without a car is to bus which takes 9h 49m and costs $80 - $130.
It takes approximately 9h 49m to get from Cape Girardeau to Topeka, including transfers.
Cape Girardeau to Topeka bus services, operated by Greyhound USA, depart from Cape Girardeau station.
Cape Girardeau to Topeka bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Cape Girardeau to Topeka is 412 miles. It takes approximately 6h 52m to drive from Cape Girardeau to Topeka.
Book your Cape Girardeau to Topeka bus tickets online with Omio.
What companies run services between Cape Girardeau, MO, USA and Topeka, KS, USA?
You can take a vehicle from Cape Girardeau to Topeka via Cape Girardeau and St Louis Bus Station in around 9h 49m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Kansas City
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $75–550
- Website
- aa.com
Flights from Cape Girardeau Municipal Airport to Manhattan Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 35m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- $240–900
Flights from Cape Girardeau Municipal Airport to Manhattan Regional Airport via Chicago O'Hare
- Ave. Duration
- 14h 19m
- When
- Every day
- Estimated price
- $80–430
Flights from Cape Girardeau Municipal Airport to Manhattan Regional Airport via Dallas/Ft.Worth, Chicago O'Hare
- Ave. Duration
- 9h 34m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- $140–650
Flights from Cape Girardeau Municipal Airport to Manhattan Regional Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 8h 31m
- When
- Monday, Friday, and Sunday
- Estimated price
- $140–420
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Kansas City
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $150–240
- Website
- Amtrak
Train from Kansas City to Topeka Station
- Ave. Duration
- 1h 44m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from St Louis Bus Station to Topeka
- Ave. Duration
- 6h 55m
- Frequency
- Twice daily
- Estimated price
- $55–85
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from 2745 Southwest Blvd - Kansas City to Quincy Street Station - Topeka
- Ave. Duration
- 52 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Omnibus Express
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Booking & Getting There
There are 30+ hotels available in Topeka.








