What is the cheapest way to get from Cape Girardeau to Tupelo?

The cheapest way to get from Cape Girardeau to Tupelo is to drive which costs $45 - $70 and takes 4h 35m.

What is the fastest way to get from Cape Girardeau to Tupelo?

The fastest way to get from Cape Girardeau to Tupelo is to drive which takes 4h 35m and costs $45 - $70.

Is there a direct bus between Cape Girardeau and Tupelo?

No, there is no direct bus from Cape Girardeau to Tupelo. However, there are services departing from Cape Girardeau and arriving at Tupelo via Memphis Bus Station. The journey, including transfers, takes approximately 6h 3m.

How far is it from Cape Girardeau to Tupelo?

The distance between Cape Girardeau and Tupelo is 285 miles. The road distance is 259.1 miles.

How do I travel from Cape Girardeau to Tupelo without a car?

The best way to get from Cape Girardeau to Tupelo without a car is to bus which takes 6h 3m and costs $60 - $110.

How long does it take to get from Cape Girardeau to Tupelo?

It takes approximately 6h 3m to get from Cape Girardeau to Tupelo, including transfers.

Where do I catch the Cape Girardeau to Tupelo bus from?

Cape Girardeau to Tupelo bus services, operated by Greyhound-us, depart from Cape Girardeau station.

Where does the Cape Girardeau to Tupelo bus arrive?

Cape Girardeau to Tupelo bus services, operated by Greyhound-us, arrive at Memphis Bus Station.

Can I drive from Cape Girardeau to Tupelo?

Yes, the driving distance between Cape Girardeau to Tupelo is 259 miles. It takes approximately 4h 35m to drive from Cape Girardeau to Tupelo.

How do I get a bus ticket from Cape Girardeau to Tupelo?

Book your Cape Girardeau to Tupelo bus tickets online with Omio.

Where can I stay near Tupelo?

There are 32+ hotels available in Tupelo.

Cape Girardeau to Tupelo - 2 ways to travel via bus, and car

How to get fromCape Girardeau to Tupelo

Travel from

See all options

Search accommodation with Expedia

There are 2 ways to get from Cape Girardeau to Tupelo by bus (Greyhound) or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Cape Girardeau to Memphis Bus Stationbus Greyhound US1173
2. Take the bus from Memphis Bus Station to Tupelobus Greyhound US0610
6h 3m
$61–107
Drive 257.6 mi
cheapest
1. Drive from Cape Girardeau to Tupelocar 257.6 mi
4h 35m
$47–68

Questions & Answers

Map of how to get from Cape Girardeau to Tupelo.

Launch map view

Distance: 283.8 mi
Duration: 6h 3m

What companies run services between Cape Girardeau, MO, USA and Tupelo, MS, USA?

You can take a vehicle from Cape Girardeau to Tupelo via Cape Girardeau, Memphis Bus Station, and Tupelo in around 6h 3m.

Operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.