What is the cheapest way to get from Cape Girardeau to Tupelo?

The cheapest way to get from Cape Girardeau to Tupelo is to drive which costs $40 - $65 and takes 4h 35m.

What is the fastest way to get from Cape Girardeau to Tupelo?

The fastest way to get from Cape Girardeau to Tupelo is to drive which takes 4h 35m and costs $40 - $65.

Is there a direct bus between Cape Girardeau and Tupelo?

No, there is no direct bus from Cape Girardeau to Tupelo. However, there are services departing from Cape Girardeau and arriving at Tupelo via Memphis Bus Station. The journey, including transfers, takes approximately 6h 8m.

How far is it from Cape Girardeau to Tupelo?

The distance between Cape Girardeau and Tupelo is 285 miles. The road distance is 259.1 miles.

How do I travel from Cape Girardeau to Tupelo without a car?

The best way to get from Cape Girardeau to Tupelo without a car is to bus which takes 6h 8m and costs $65 - $100.

How long does it take to get from Cape Girardeau to Tupelo?

It takes approximately 6h 8m to get from Cape Girardeau to Tupelo, including transfers.

Where do I catch the Cape Girardeau to Tupelo bus from?

Cape Girardeau to Tupelo bus services, operated by Greyhound USA, depart from Cape Girardeau station.

Bus or fly from Cape Girardeau to Tupelo?

The best way to get from Cape Girardeau to Tupelo is to bus which takes 6h 8m and costs $65 - $100. Alternatively, you can fly, which costs $450 - $1,400 and takes 5h 1m.

Where does the Cape Girardeau to Tupelo bus arrive?

Cape Girardeau to Tupelo bus services, operated by Greyhound USA, arrive at Memphis Bus Station.

Can I drive from Cape Girardeau to Tupelo?

Yes, the driving distance between Cape Girardeau to Tupelo is 259 miles. It takes approximately 4h 35m to drive from Cape Girardeau to Tupelo.

How do I get a bus ticket from Cape Girardeau to Tupelo?

Book your Cape Girardeau to Tupelo bus tickets online with Omio.

Where can I stay near Tupelo?

There are 35+ hotels available in Tupelo.

Cape Girardeau to Tupelo - 3 ways to travel via bus, car, and plane

How to get fromCape Girardeau to Tupelo

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There are 3 ways to get from Cape Girardeau to Tupelo by bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus (Greyhound)
best
1. Take the bus from Cape Girardeau to Memphis Bus Stationbus Greyhound US1173
2. Take the bus from Memphis Bus Station to Tupelobus Greyhound US0610
6h 8m
$66–100
Drive 257.6 mi
cheapest
1. Drive from Cape Girardeau to Tupelocar 257.6 mi
4h 35m
$44–64
Fly
1. Fly from Cape Girardeau Municipal Airport (CGI) to Tupelo Regional Airport (TUP)plane CGI - TUP
5h 1m
$458–1,346

Cape Girardeau Municipal Airport (CGI) to Tupelo Regional Airport (TUP) flights

4Weekly Planes

4h 40mAverage Duration

$420Cheapest Price

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Comparing Your Travel Options

Map of how to get from Cape Girardeau to Tupelo.

Launch map view

Distance: 283.8 mi
Duration: 6h 8m

What companies run services between Cape Girardeau, MO, USA and Tupelo, MS, USA?

You can take a vehicle from Cape Girardeau to Tupelo via Cape Girardeau, Memphis Bus Station, and Tupelo in around 6h 8m. Alternatively, Corporate Flight Management Inc flies from Cape Girardeau Municipal Airport (CGI) to Tupelo Regional Airport (TUP) 4 times a week.

Airlines

Bus operators

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