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How to get fromCarbondale to Buffaloby plane, train, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Carbondale to Buffalo by plane, train, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Williamson County Regional Airport

    best
    1. Fly from Williamson County Regional Airport (MWA) to Buffalo Niagara International Airport (BUF)plane plane MWA - BUF
    6h 31m
    $185–818

  2. Drive 745.6 mi

    cheapest
    1. Drive from Carbondale to Buffalocar car 745.6 mi
    13h 3m
    $137–197

  3. Train, bus

    1. Take the train from Carbondale to Chicago Union Stationtrain train
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    17h 44m
    $150–343

  4. Train (Amtrak)

    1. Take the train from Carbondale to Chicago Union Stationtrain train Saluki / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    18h 14m
    $274–693

  5. Drive to Barkley Regional Airport, fly

    1. Drive from Carbondale to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Buffalo Niagara International Airport (BUF)plane plane PAH - BUF
    9h 25m
    $144–747

  6. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Carbondale to St. Louisbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)plane plane STL - BUF
    8h 3m
    $170–929

  7. Bus

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Buffalobus bus
    21h 40m
    $147–283

Carbondale to Buffalo by train, foot, and bus

Calendar7Weekly Services
Duration17h 44mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

Map of how to get from Carbondale to Buffalo.ExpandLaunch map view
  • Distance: 674.6 mi
  • Duration: 6h 31m

What companies run services between Carbondale, IL, USA and Buffalo, NY, USA?

American Airlines, Corporate Flight Management Inc, and United Airlines fly from Williamson County Regional Airport (MWA) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, you can take a train from Carbondale to Buffalo via Chicago Union Station and Buffalo Depew Station in around 18h 14m.

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