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How to get fromCarbondale to Charlestonby plane, bus (Flixbus, Greyhound), car, or bus

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There are 5 ways to get from Carbondale to Charleston by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Williamson County Regional Airport

    best
    1. Fly from Williamson County Regional Airport (MWA) to Charleston International Airport (CHS)plane plane MWA - CHS
    6h 43m
    $155–641

  2. Bus to Lambert–St. Louis International Airport, fly

    cheapest
    1. Take the bus from Carbondale to St. Louisbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Charleston International Airport (CHS)plane plane STL - CHS
    7h 12m
    $121–601

  3. Bus

    1. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus FlixBus N2521
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    22h 14m
    $147–265

  4. Drive 734.8 mi

    1. Drive from Carbondale to Charlestoncar car 734.8 mi
    13h 1m
    $135–194

  5. Bus to Nashville, fly

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Fly from Nashville (BNA) to Charleston International Airport (CHS)plane plane BNA - CHS
    8h 33m
    $387–1,159

Carbondale to Charleston by bus

Calendar5Weekly Buses
Duration22h 14mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Carbondale to Charleston.ExpandLaunch map view
  • Distance: 633.1 mi
  • Duration: 6h 43m

What companies run services between Carbondale, IL, USA and Charleston, SC, USA?

American Airlines and Corporate Flight Management Inc fly from Williamson County Regional Airport (MWA) to Charleston International Airport (CHS) 4 times a day. Alternatively, you can take a bus from Carbondale Intermodal Station to Transit Mall via Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 22h 14m.

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