Rome2Rio

How to get fromCarbondale to Des Moinesby plane, bus (Amtrak, Flixbus, Greyhound), car, bus, or train

Find Transport to Des Moines

See all options

There are 6 ways to get from Carbondale to Des Moines by plane, bus (Amtrak, Flixbus, Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Williamson County Regional Airport

    best
    1. Fly from Williamson County Regional Airport (MWA) to Des Moines (DSM)plane plane MWA - DSM
    5h 6m
    $170–760

  2. Drive 424.3 mi

    cheapest
    1. Drive from Carbondale to Des Moinescar car 424.3 mi
    8h 37m
    $78–112

  3. Bus

    1. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    2. Take the bus from St Louis Bus Station to Des Moinesbus bus Greyhound US0153S
    11h 30m
    $80–176

  4. Drive to Barkley Regional Airport, fly

    1. Drive from Carbondale to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Des Moines (DSM)plane plane PAH - DSM
    6h 54m
    $139–639

  5. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Carbondale to St. Louisbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane plane STL - DSM
    7h 14m
    $175–820

  6. Train, bus

    1. Take the train from Carbondale to Champaign-Urbanatrain train Illini / ...
    2. Take the bus from Champaign Intermodal Trans Ctr to Des Moinesbus bus Greyhound US0157S
    11h 35m
    $114–228

Carbondale to Des Moines by bus

Calendar7Weekly Buses
Duration11h 30mAverage Duration
Ticket$80Cheapest Price
See schedules

Questions & Answers

Map of how to get from Carbondale to Des Moines.ExpandLaunch map view
  • Distance: 378.1 mi
  • Duration: 5h 6m

What companies run services between Carbondale, IL, USA and Des Moines, IA, USA?

American Airlines, Corporate Flight Management Inc, and two other airlines fly from Williamson County Regional Airport (MWA) to Des Moines (DSM) 5 times a day. Alternatively, you can take a bus from Carbondale to Des Moines via St. Louis and St Louis Bus Station in around 11h 30m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers