Rome2Rio

How to get fromCarbondale to Louisvilleby bus (Flixbus, Greyhound), car, plane, train, or bus

Find Transport to Louisville

See all options

There are 6 ways to get from Carbondale to Louisville by bus (Flixbus, Greyhound), car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Carbondale Intermodal Station to Clarksville Park & Ridebus bus FlixBus N2521
    2. Take the bus from Clarksville Park & Ride to Louisville Bus Stationbus bus Greyhound US0112
    7h 35m
    $53–82

  2. Drive  215 mi

    cheapest
    1. Drive from Carbondale to Louisvillecar car 215 mi
    4h 5m
    $40–57

  3. Fly from Williamson County Regional Airport

    1. Fly from Williamson County Regional Airport (MWA) to Louisville International Airport (SDF)plane plane MWA - SDF
    6h 3m
    $164–792

  4. Train, bus

    1. Take the train from Carbondale to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    8h 40m
    $88–189

  5. Drive to Barkley Regional Airport, fly

    1. Drive from Carbondale to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Louisville International Airport (SDF)plane plane PAH - SDF
    9h 16m
    $123–671

  6. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Carbondale to St. Louisbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane plane STL - SDF
    7h 59m
    $119–736

Carbondale to Louisville by bus

Calendar5Weekly Buses
Duration7h 35mAverage Duration
Ticket$53Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Carbondale to Louisville.ExpandLaunch map view
  • Distance: 342.1 mi
  • Duration: 7h 35m

What companies run services between Carbondale, IL, USA and Louisville, KY, USA?

You can take a bus from Carbondale Intermodal Station to Louisville Bus Station via Clarksville Park & Ride in around 7h 35m. Alternatively, American Airlines flies from Williamson County Regional Airport (MWA) to Louisville International Airport (SDF) 3 times a day.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There