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How to get fromCarlisle to Hyannisby bus, train, car, taxi, or plane

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There are 7 ways to get from Carlisle to Hyannis by bus, train, car, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 62 bus, bus

    best
    1. Take the bus from South Rd opp Crescent Ave to Alewifebus bus 62
    2. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus Boston
    3h 41m
    $37–69

  2. Drive 91.5 mi

    cheapest
    1. Drive from Carlisle to Hyanniscar car 91.5 mi
    2h 1m
    $17–25

  3. Train

    1. Take the train from South Station to Hyannistrain train CapeFLYER
    4h 38m
    $34–61

  4. Taxi, train, fly

    1. Take the taxi from Carlisle to North Billericataxi taxi
    2. Take the train from North Billerica to Anderson/Woburntrain train
    3. Fly from Boston Logan Airport (BOS) to Barnstable Municipal Airport (HYA)plane plane BOS - HYA
    3h 1m
    $152–353

  5. Line 62 bus, bus via Bedford VA Hospital @ Middlesex CC - Bldg 10

    1. Take the bus from Bedford VA Hospital @ Middlesex CC - Bldg 10 to Alewifebus bus 62
    2. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus Hyannis - South Shore to Logan Airport
    3h 45m
    $51–67

  6. Line 62 bus, bus via Bedford VA Hospital @ Middlesex CC - Bldg 10 #2

    1. Take the bus from Bedford VA Hospital @ Middlesex CC - Bldg 10 to Alewifebus bus 62
    2. Take the bus from Boston to Hyannisbus bus Bz 0956 / ...
    3h 58m
    $39–72

  7. Line 354 bus, bus

    1. Take the bus from Chestnut Ave @ Cambridge St to State St @ Washington Mall - State St Stabus bus 354
    2. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus Boston
    4h 1m
    $49–84

Boston Logan Airport (BOS) to Barnstable Municipal Airport (HYA) flights

Calendar34Weekly Planes
Duration1h 10mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from Carlisle to Hyannis.ExpandLaunch map view
  • Distance: 94.4 mi
  • Duration: 3h 41m

What companies run services between Carlisle, MA, USA and Hyannis, MA, USA?

You can take a vehicle from Carlisle to Hyannis Transportation Center via South Rd opp Crescent Ave, Alewife, Alewife, South Station, and Boston South Station in around 3h 41m. Alternatively, Cape Flyer operates a train from South Station to Hyannis 3 times a week. Tickets cost $5–22 and the journey takes 2h 30m.

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