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How to get fromCarlisle to Portlandby train (Amtrak), bus (Amtrak), car, or bus (Flixbus, Greyhound)

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There are 4 ways to get from Carlisle to Portland by train (Amtrak), bus (Amtrak), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Woburn Amtrak Station to Portlandtrain train Downeaster
    3h 37m
    $53–104
  2. Drive 105.3 mi

    cheapest
    1. Drive from Carlisle to Portlandcar car 105.3 mi
    1h 54m
    $20–28
  3. Line 354 bus, bus

    1. Take the bus from Chestnut Ave @ Cambridge St to State St @ Washington Mall - State St Stabus bus 354
    2. Take the bus from Boston, MA - South Station to Portland, MEbus bus Logan Airport / ...
    3h 40m
    $55–89
  4. Bus

    1. Take the bus from Boston to City of Portlandbus bus FlixBus N2615
    4h 13m
    $39–62

Questions & Answers

What companies run services between Carlisle, MA, USA and Portland, ME, USA?

Amtrak operates a train from Woburn Amtrak Station to Portland 5 times a day. Tickets cost $30–70 and the journey takes 2h 12m. Alternatively, you can take a vehicle from Carlisle to Portland, ME via Chestnut Ave @ Cambridge St, State St @ Washington Mall - State St Sta, and Boston, MA - South Station in around 3h 40m.

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