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How to get fromCarlisle to Bostonby bus, plane, train (Amtrak), bus (Flixbus), car, train, or bus (Greyhound)

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There are 6 ways to get from Carlisle to Boston by bus, plane, train (Amtrak), bus (Flixbus), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Harrisburg International Airport, fly

    best
    1. Take the bus from Hanover St & High St to Market Square Transfer Centerbus bus
    2. Fly from Harrisburg International Airport (MDT) to Boston Logan Airport (BOS)plane plane MDT - BOS
    4h 23m
    $103–654

  2. Bus via New York

    cheapest
    1. Take the bus from Harrisburg Bus Station to Port Authority Bus Terminalbus bus Greyhound US0421 / ...
    2. Take the bus from Port Authority Bus Terminal to South Stationbus bus New York
    12h 27m
    $67–142

  3. Train (Amtrak)

    1. Take the train from Harrisburg to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train Acela
    9h 58m
    $137–292

  4. Bus (Flixbus)

    1. Take the bus from Harrisburg Bus Station to New York Midtownbus bus FlixBus N2640 / ...
    2. Take the bus from New York Midtown to Bostonbus bus FlixBus 2610 / ...
    11h 24m
    $72–122

  5. Drive 391 mi

    1. Drive from Carlisle to Bostoncar car 391 mi
    7h 31m
    $72–104

  6. Bus, train to Philadelphia International Airport, fly

    1. Take the bus from Hanover St & High St to Market Square Transfer Centerbus bus
    2. Take the train from Harrisburg to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Boston Logan Airport (BOS)plane plane PHL - BOS
    6h 40m
    $205–1,025

Carlisle to Boston by bus, foot, and train (Amtrak)

Calendar81Weekly Services
Duration9h 58mAverage Duration
Ticket$137Cheapest Price
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Questions & Answers

Map of how to get from Carlisle to Boston.ExpandLaunch map view
  • Distance: 364.2 mi
  • Duration: 4h 23m

What companies run services between Carlisle, PA, USA and Boston, MA, USA?

You can take a bus from Hanover St & High St to Boston via Market Square Transfer Center, Harrisburg, and Ny Moynihan Train Hall At Penn Station in around 9h 58m. Alternatively, you can take a bus from Hanover St & High St to Boston via Market Square Transfer Center, Harrisburg Bus Station, and New York Midtown in around 11h 24m.

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