There are 5 ways to get from Carlisle to Buffalo by bus (Greyhound), car, train, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Harrisburg, Pa to Scranton, Pabus 770
- Take the bus from Scranton Bus Station to Buffalobus Greyhound US0205 / ...
11h 56m$66–157Drive 268.8 mi
cheapest- Drive from Carlisle to Buffalocar 268.8 mi
6h 17m$50–71Train to Philadelphia International Airport, fly
- Take the train from Harrisburg to 30th Street Stationtrain
- Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane PHL - BUF
7h 47m$132–754Bus via Sandy
- Take the bus from Harrisburg, Pa to Dubois, Pabus 731
- Take the bus from DuBois to Buffalobus Fab510
12h 26m$59–202Train, train to Baltimore-Washington International Airport, fly
- Take the train from Harrisburg to 30th Street Stationtrain
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane BWI - BUF
8h 46m$138–1,301
Carlisle to Buffalo by bus and foot
Questions & Answers
The cheapest way to get from Carlisle to Buffalo is to drive which costs $45 - $75 and takes 6h 17m.
The fastest way to get from Carlisle to Buffalo is to drive which takes 6h 17m and costs $45 - $75.
No, there is no direct bus from Carlisle to Buffalo. However, there are services departing from Hanover St & High St and arriving at Buffalo via Harrisburg, Pa and Scranton Bus Station. The journey, including transfers, takes approximately 11h 56m.
The distance between Carlisle and Buffalo is 418 miles. The road distance is 270.4 miles.
The best way to get from Carlisle to Buffalo without a car is to bus which takes 11h 56m and costs $65 - $160.
It takes approximately 11h 56m to get from Carlisle to Buffalo, including transfers.
Carlisle to Buffalo bus services, operated by Trailways, depart from Harrisburg, Pa station.
Carlisle to Buffalo bus services, operated by Trailways, arrive at Scranton, Pa station.
Yes, the driving distance between Carlisle to Buffalo is 270 miles. It takes approximately 6h 17m to drive from Carlisle to Buffalo.
There are 248+ hotels available in Buffalo.
What companies run services between Carlisle, PA, USA and Buffalo, NY, USA?
You can take a bus from Hanover St & High St to Buffalo via Market Square Transfer Center, Harrisburg, Pa, and Scranton Bus Station in around 11h 56m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $80–550
- Website
- aa.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $95–650
Flights from Philadelphia International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–700
- Website
- united.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $110–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Harrisburg to 30th Street Station
- Ave. Duration
- 1h 44m
- Frequency
- Every 2 hours
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
Train from Harrisburg to 30th Street Station
- Ave. Duration
- 1h 44m
- Frequency
- Every 2 hours
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $24–460
- First Class
- $140–650
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Harrisburg, Pa to Scranton, Pa
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $24–75
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $24–75
- Flexible
- $45–75
Bus from Harrisburg, Pa to Dubois, Pa
- Ave. Duration
- 4h 45m
- Frequency
- Once a week
- Estimated price
- $27–90
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $27–85
- Flexible
- $50–90
Bus from DuBois to Buffalo
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- $30–110
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $30–110
- Flexible
- $60–110
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Scranton Bus Station to Buffalo
- Ave. Duration
- 5h 40m
- Frequency
- 4 times a day
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from DuBois to Buffalo
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.fullingtontours.com
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