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How to get fromCarlisle to Indianapolisby plane, bus (Flixbus), car, train, or bus (Greyhound)

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There are 5 ways to get from Carlisle to Indianapolis by plane, bus (Flixbus), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Indianapolis (IND)plane plane MDT - IND
    7h 36m
    $205–1,106
  2. Bus via Indianapolis Union Station (Greyhound)

    cheapest
    1. Take the bus from Harrisburg Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    15h 21m
    $87–162
  3. Bus (Flixbus)

    1. Take the bus from Harrisburg Bus Station to Indianapolisbus bus FlixBus N2642 / ...
    14h 21m
    $92–162
  4. Drive 524.6 mi

    1. Drive from Carlisle to Indianapoliscar car 524.6 mi
    9h 7m
    $96–139
  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Indianapolis (IND)plane plane PHL - IND
    8h 33m
    $157–927

Carlisle to Indianapolis by bus and foot (Flixbus)

Calendar18Weekly Services
Duration14h 21mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

What companies run services between Carlisle, PA, USA and Indianapolis, IN, USA?

United Airlines, American Airlines, and Delta fly from Harrisburg International Airport (MDT) to Indianapolis (IND) hourly. Alternatively, Flixbus USA operates a bus from Harrisburg Bus Station to Indianapolis 3 times a day. Tickets cost $90–160 and the journey takes 12h 20m.

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