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How to get fromCarlisle to Jacksonvilleby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), or car

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There are 4 ways to get from Carlisle to Jacksonville by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly

    best
    1. Take the bus from Hanover St & High St to Market Square Transfer Centerbus bus
    2. Fly from Harrisburg International Airport (MDT) to Jacksonville (JAX)plane plane MDT - JAX
    6h 28m
    $89–457
  2. Bus

    1. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0430
    2. Take the bus from Baltimore Downtown Bus Station to Jacksonvillebus bus FlixBus N2472
    19h 46m
    $123–224
  3. Train (Amtrak)

    1. Take the train from Harrisburg to 30th Street Stationtrain train Keystone Service / ...
    2. Take the train from 30th Street Station to Jacksonvilletrain train Silver Meteor
    22h 42m
    $303–675
  4. Drive 807.4 mi

    1. Drive from Carlisle to Jacksonvillecar car 807.4 mi
    13h 46m
    $148–213

Carlisle to Jacksonville by bus and foot

Calendar5Weekly Services
Duration19h 46mAverage Duration
Ticket$123Cheapest Price
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Questions & Answers

What companies run services between Carlisle, PA, USA and Jacksonville, FL, USA?

You can take a bus from Hanover St & High St to Jacksonville via Market Square Transfer Center, Harrisburg Bus Station, and Baltimore Downtown Bus Station in around 19h 46m. Alternatively, you can take a bus from Hanover St & High St to Jefferson St + Beaver St via Market Square Transfer Center, Harrisburg, 30th Street Station, Jacksonville, and Amtrak Station in around 22h 42m.

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