There are 8 ways to get from Carlisle to Worcester by bus, plane, train, bus (Flixbus), car, bus (Greyhound), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Harrisburg International Airport, fly to Boston Logan Airport, bus
best- Take the bus from Hanover St & High St to Market Square Transfer Centerbus
- Fly from Harrisburg International Airport (MDT) to Boston Logan Airport (BOS)plane MDT - BOS
- Take the bus from Boston to Worcesterbus
6h 43m$55–339Train, bus
- Take the train from Harrisburg to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to New Haventrain
- Take the train from New Haven to Hartford Amtrak Stationtrain
- Take the bus from Hartford to Worcesterbus
11h 32m$98–791Bus via New York
- Take the bus from Harrisburg Bus Station to New York City Chinatownbus FlixBus N2640
- Take the bus from New York, NY - 1st Avenue between East 38th and 39th Streets to Worcester, MA - Union Stationbus Jersey City
11h 45m$85–195Drive 352.9 mi
- Drive from Carlisle to Worcestercar 352.9 mi
6h 48m$65–93Train to Philadelphia International Airport, fly to Worcester Regional Airport
- Take the train from Harrisburg to 30th Street Stationtrain
- Fly from Philadelphia International Airport (PHL) to Worcester Regional Airport (ORH)plane PHL - ORH
8h 13m$92–477Bus
- Take the bus from Harrisburg Bus Station to Port Authority Bus Terminalbus Greyhound US0421 / ...
- Take the bus from New York to Worcesterbus Ppb 5613 / ...
11h 46m$72–162Train via Springfield (Amtrak)
- Take the train from Harrisburg to Newark Penn Stationtrain
- Take the train from Newark Penn Station to Springfieldtrain
- Take the train from Springfield to Worcester Union Stationtrain
12h 32m$118–252Train
- Take the train from Harrisburg to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
- Take the train from Lansdowne to Worcestertrain
12h 34m$134–297
Carlisle to Worcester by bus, foot, and train
Questions & Answers
The cheapest way to get from Carlisle to Worcester is to drive which costs $60 - $95 and takes 6h 48m.
The fastest way to get from Carlisle to Worcester is to bus and fly which takes 6h 43m and costs $55 - $340.
No, there is no direct bus from Carlisle to Worcester station. However, there are services departing from Hanover St & High St and arriving at Worcester, MA - Union Station via Harrisburg Bus Station, Pike St/Division St and New York, NY - 1st Avenue between East 38th and 39th Streets. The journey, including transfers, takes approximately 11h 45m.
No, there is no direct train from Carlisle to Worcester station. However, there are services departing from Harrisburg and arriving at Worcester Union Station via Newark Penn Station and Springfield. The journey, including transfers, takes approximately 12h 32m.
The distance between Carlisle and Worcester is 415 miles. The road distance is 355 miles.
The best way to get from Carlisle to Worcester without a car is to train and bus which takes 11h 32m and costs $95 - $800.
It takes approximately 6h 43m to get from Carlisle to Worcester, including transfers.
Carlisle to Worcester bus services, operated by Flixbus USA, depart from Harrisburg Bus Station.
Carlisle to Worcester train services, operated by Amtrak, depart from Harrisburg station.
The best way to get from Carlisle to Worcester is to bus via New York which takes 11h 45m and costs $85 - $200. Alternatively, you can train via Springfield, which costs $110 - $260 and takes 12h 32m.
What companies run services between Carlisle, PA, USA and Worcester, MA, USA?
You can take a bus from Hanover St & High St to Worcester, MA - Union Station via Market Square Transfer Center, Harrisburg Bus Station, New York City Chinatown, Pike St/Division St, and New York, NY - 1st Avenue between East 38th and 39th Streets in around 11h 45m. Alternatively, you can take a bus from Hanover St & High St to Worcester Union Station via Market Square Transfer Center, Harrisburg, Newark Penn Station, and Springfield in around 12h 32m.
- Website
- aa.com
Flights from Harrisburg International Airport to Boston Logan Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $45–310
Flights from Harrisburg International Airport to Boston Logan Airport via Philadelphia International Airport
- Ave. Duration
- 3h 26m
- When
- Every day
- Estimated price
- $50–320
Flights from Philadelphia International Airport to Worcester Regional Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $55–400
- Website
- united.com
Flights from Harrisburg International Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $55–340
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Harrisburg to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 29m
- Frequency
- Every 2 hours
- Estimated price
- $55–130
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to New Haven
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- $23–50
- Website
- Amtrak
Train from New Haven to Hartford Amtrak Station
- Ave. Duration
- 44 min
- Frequency
- Every 3 hours
- Estimated price
- $11–24
- Website
- Amtrak
Train from Harrisburg to 30th Street Station
- Ave. Duration
- 1h 44m
- Frequency
- Every 2 hours
- Estimated price
- $30–70
- Website
- Amtrak
Train from Harrisburg to Newark Penn Station
- Ave. Duration
- 3h 7m
- Frequency
- Every 2 hours
- Estimated price
- $55–120
- Website
- Amtrak
Train from Newark Penn Station to Springfield
- Ave. Duration
- 3h 58m
- Frequency
- 3 times a day
- Estimated price
- $45–95
- Website
- Amtrak
Train from Springfield to Worcester Union Station
- Ave. Duration
- 1h 26m
- Frequency
- Once daily
- Estimated price
- $16–35
- Website
- Amtrak
Train from Harrisburg to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 29m
- Frequency
- Every 2 hours
- Estimated price
- $55–130
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 14m
- Frequency
- Every 3 hours
- Estimated price
- $70–150
- Website
- Amtrak
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to New Haven
- Ave. Duration
- 1h 43m
- Frequency
- Every 4 hours
- Estimated price
- $17–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $17–450
- First Class
- $120–600
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Lansdowne to Worcester
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $6–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $6–9
- Phone
- +1 800-632-9063
- Website
- Rabbit Transit
Bus from Hanover St & High St to Market Square Transfer Center
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- $1–2
- Website
- Rabbit Transit
- Adult
- $1–2
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Boston to Worcester
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $9–22
- Website
- Peter Pan
Bus from Hartford to Worcester
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $13–35
- Website
- Peter Pan
Bus from New York to Worcester
- Ave. Duration
- 3h 25m
- Frequency
- 5 times a day
- Estimated price
- $35–90
- Website
- Peter Pan
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Worcester
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Estimated price
- $6–13
- Website
- Greyhound
Bus from Harrisburg Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 5h 20m
- Frequency
- Every 4 hours
- Estimated price
- $35–70
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Worcester
- Ave. Duration
- 55 min
- Frequency
- 5 times a week
- Estimated price
- $6–11
- Schedules at
- Flixbus USA
Bus from Harrisburg Bus Station to New York City Chinatown
- Ave. Duration
- 4h 45m
- Frequency
- 6 times a week
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
- Phone
- +1-844-800-6828
- [email protected]
- Website
- OurBus
Bus from New York, NY - 1st Avenue between East 38th and 39th Streets to Worcester, MA - Union Station
- Ave. Duration
- 3h 30m
- Frequency
- 6 times a week
- Estimated price
- $50–130
- Website
- OurBus
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More Questions & Answers
Carlisle to Worcester bus services, operated by Flixbus USA, arrive at New York City Chinatown station.
Carlisle to Worcester train services, operated by Amtrak, arrive at Newark Penn Station.
Yes, the driving distance between Carlisle to Worcester is 355 miles. It takes approximately 6h 48m to drive from Carlisle to Worcester.
There are 73+ hotels available in Worcester.


















