Rome2Rio

How to get fromCary to Chicago Union Stationby bus, plane, subway, train (Amtrak), bus (Flixbus, Greyhound), car, or train

Find Transport to Chicago Union Station

See all options

There are 6 ways to get from Cary to Chicago Union Station by bus, plane, subway, train (Amtrak), bus (Flixbus, Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 310 bus to Raleigh-Durham International Airport, fly to Chicago Midway International Airport, subway

    best
    1. Take the bus from Cary Depot to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    3. Take the subway from Midway to Quincysubway subway
    4h 47m
    $158–220

  2. Line 310 bus to Raleigh-Durham International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Cary Depot to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane plane RDU - ORD
    5h 25m
    $62–320

  3. Train (Amtrak)

    1. Take the train from Cary to Chicago Union Stationtrain train Floridian
    25h 12m
    $550–950

  4. Bus

    1. Take the bus from Durham to Washington Union Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Washington Union Station to Chicago Bus Stationbus bus Greyhound US0164
    25h 43m
    $166–266

  5. Drive  782 mi

    1. Drive from Cary to Chicago Union Stationcar car 782 mi
    13h 50m
    $143–207

  6. Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Cary to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    5h 48m
    $132–466

Cary to Chicago Union Station by train (Amtrak)

Calendar7Weekly Trains
Duration25h 12mAverage Duration
Ticket$550Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Cary to Chicago Union Station.ExpandLaunch map view
  • Distance: 656.6 mi
  • Duration: 4h 47m

What companies run services between Cary, NC, USA and Chicago Union Station, IL, USA?

Amtrak operates a train from Cary to Chicago Union Station once daily. Tickets cost $550–950 and the journey takes 25h 12m. Alternatively, you can take a bus from Cary Depot to Chicago Union Station via Regional Transit Center, Durham Station, Durham, Washington Union Station, and Chicago Bus Station in around 25h 43m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There