There are 7 ways to get from Cary to Indianapolis by bus, plane, train, train (Amtrak), car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 310 bus to Raleigh-Durham International Airport, fly
best- Take the bus from Cary Depot to Regional Transit Centerbus
- Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane RDU - IND
5h 1m$168–378Train, bus
cheapest- Take the train from Cary to Greensborotrain
- Take the bus from Greensboro to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Columbus to Indianapolis Union Stationbus
18h 26m$92–186Train (Amtrak)
- Take the train from Cary to Greensborotrain
- Take the train from Greensboro to Charlottesvilletrain
- Take the train from Charlottesville to Indianapolistrain
22h 9m$208–502Drive 604.8 mi
- Drive from Cary to Indianapoliscar 604.8 mi
10h 47m$111–160Train to Charlotte Douglas International Airport, fly
- Take the train from Cary to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane CLT - IND
7h 47m$134–654Bus
- Take the bus from Durham to Atlanta Bus Stationbus FlixBus N2471 / ...
- Take the bus from Atlanta Bus Station to Indianapolisbus FlixBus 2512
22h 29m$140–230Train via Arlington (Amtrak)
- Take the train from Cary to Alexandriatrain Floridian / ...
- Take the train from Alexandria to Indianapolistrain Cardinal
25h 6m$244–595
Cary to Indianapolis by train and bus
Comparing Your Travel Options
The cheapest way to get from Cary to Indianapolis is to drive which costs $110 - $160 and takes 10h 47m.
The fastest way to get from Cary to Indianapolis is to line 310 bus and fly which takes 5h 1m and costs $160 - $380.
No, there is no direct bus from Cary to Indianapolis. However, there are services departing from Cary Depot and arriving at Indianapolis via Regional Transit Center, Durham and Atlanta Bus Station. The journey, including transfers, takes approximately 22h 29m.
No, there is no direct train from Cary to Indianapolis. However, there are services departing from Cary and arriving at Indianapolis via Greensboro and Charlottesville. The journey, including transfers, takes approximately 22h 9m.
The distance between Cary and Indianapolis is 520 miles. The road distance is 608.3 miles.
The best way to get from Cary to Indianapolis without a car is to train and bus which takes 18h 26m and costs $90 - $190.
It takes approximately 5h 1m to get from Cary to Indianapolis, including transfers.
Cary to Indianapolis bus services, operated by Flixbus USA, depart from Durham station.
Cary to Indianapolis train services, operated by Amtrak, depart from Cary station.
The best way to get from Cary to Indianapolis is to train which takes 22h 9m and costs $200 - $500. Alternatively, you can bus, which costs $140 - $230 and takes 22h 29m.
What companies run services between Cary, NC, USA and Indianapolis, IN, USA?
You can take a train from Cary to Indianapolis via Greensboro and Charlottesville in around 22h 9m. Alternatively, you can take a bus from Cary Depot to Indianapolis via Regional Transit Center, Durham Station, Durham, and Atlanta Bus Station in around 22h 29m.
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Indianapolis via Baltimore
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $120–650
Flights from Raleigh-Durham International Airport to Indianapolis via Chicago Midway
- Ave. Duration
- 4h 2m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $120–650
Flights from Charlotte Douglas International Airport to Indianapolis via Chicago Midway
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Cary to Greensboro
- Ave. Duration
- 1h 21m
- Frequency
- 5 times a day
- Estimated price
- $17–45
- Website
- Amtrak
Train from Cary to Greensboro
- Ave. Duration
- 1h 21m
- Frequency
- 5 times a day
- Estimated price
- $17–45
- Website
- Amtrak
Train from Greensboro to Charlottesville
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $40–100
- Website
- Amtrak
Train from Charlottesville to Indianapolis
- Ave. Duration
- 15h 23m
- Frequency
- 3 times a week
- Estimated price
- $150–360
- Website
- Amtrak
Train from Cary to Charlotte Amtrak Station
- Ave. Duration
- 2h 58m
- Frequency
- 5 times a day
- Estimated price
- $40–100
- Website
- Amtrak
Train from Cary to Alexandria
- Ave. Duration
- 6h 10m
- Frequency
- Twice daily
- Estimated price
- $70–180
- Website
- Amtrak
Train from Alexandria to Indianapolis
- Ave. Duration
- 17h 56m
- Frequency
- 3 times a week
- Estimated price
- $170–420
- Website
- Amtrak
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from Cary Depot to Regional Transit Center
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
Want to know more about travelling around United States
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Booking & Getting There
Cary to Indianapolis bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Cary to Indianapolis train services, operated by Amtrak, arrive at Greensboro station.
Yes, the driving distance between Cary to Indianapolis is 608 miles. It takes approximately 10h 47m to drive from Cary to Indianapolis.
Book your Cary to Indianapolis train tickets online with Omio.
There are 880+ hotels available in Indianapolis.





