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How to get fromCary to Knoxvilleby plane, train, bus, taxi, shuttle, or car

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There are 6 ways to get from Cary to Knoxville by plane, train, bus, taxi, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Mcghee Tyson Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Mcghee Tyson Airport (TYS)plane plane RDU - TYS
    5h 35m
    $156–726

  2. Drive 334.6 mi

    cheapest
    1. Drive from Cary to Knoxvillecar car 334.6 mi
    6h 36m
    $62–89

  3. Train, bus, taxi, shuttle, drive

    1. Take the train from Cary to High Pointtrain train
    2. Take the bus from Forsyth Hospital to Boonebus bus
    3. Take the taxi from Boone to Black Bear Resorttaxi taxi
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Knoxvillecar car
    11h 6m
    $331–411

  4. Train to Charlotte Douglas International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Cary to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Mcghee Tyson Airport (TYS)plane plane CLT - TYS
    6h 41m
    $205–833

  5. Fly Raleigh-Durham International Airport to Nashville, drive

    1. Fly from Raleigh-Durham International Airport (RDU) to Nashville (BNA)plane plane RDU - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 21m
    $426–1,156

  6. Train, bus, shuttle, drive

    1. Take the train from Cary to High Pointtrain train
    2. Take the bus from Forsyth Hospital to Boonebus bus
    3. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Knoxvillecar car
    11h 36m
    $297–347

Raleigh-Durham International Airport (RDU) to Mcghee Tyson Airport (TYS) flights

Calendar128Weekly Planes
Duration3h 55mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Cary to Knoxville.ExpandLaunch map view
  • Distance: 317.9 mi
  • Duration: 5h 35m

What companies run services between Cary, NC, USA and Knoxville, TN, USA?

Delta, American Airlines, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Mcghee Tyson Airport (TYS) hourly.

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