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How to get fromCary to Louisvilleby bus, plane, bus (Flixbus, Greyhound, Amtrak), train, or car

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There are 6 ways to get from Cary to Louisville by bus, plane, bus (Flixbus, Greyhound, Amtrak), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 310 bus, bus, fly

    best
    1. Take the bus from Cary Depot to Regional Transit Centerbus bus
    2. Take the bus from Regional Transit Center to RDU Airport at Terminal 1bus bus
    3. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane plane RDU - SDF
    4h 44m
    $96–558

  2. Bus

    cheapest
    1. Take the bus from Health Sciences Library on S Columbia to Coble Transportation Centerbus bus 4
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    21h 10m
    $68–162

  3. Bus via Atlanta

    1. Take the bus from Durham to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    19h 44m
    $130–250

  4. Train, bus (Amtrak)

    1. Take the train from Cary to Greensborotrain train
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    25h 34m
    $291–613

  5. Drive 514.3 mi

    1. Drive from Cary to Louisvillecar car 514.3 mi
    9h 48m
    $94–136

  6. Train, bus via Toledo

    1. Take the train from Cary to Toledotrain train
    2. Take the bus from Toledo Bus Stop to Cincinnati Bus Stationbus bus
    3. Take the bus from Greyhound Station Cincinnati to Louisville, KY Bus Stationbus bus
    27h 50m
    $305–660

Cary to Louisville by bus

Calendar14Weekly Buses
Duration19h 44mAverage Duration
Ticket$130Cheapest Price
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Questions & Answers

Map of how to get from Cary to Louisville.ExpandLaunch map view
  • Distance: 435.1 mi
  • Duration: 4h 44m

What companies run services between Cary, NC, USA and Louisville, KY, USA?

You can take a bus from Cary Depot to Louisville, KY via Regional Transit Center, Durham Station, Durham, Atlanta Bus Station, and Nashville in around 19h 44m.

Airlines
Train operators
Bus operators

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