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How to get fromCasper to Knoxvilleby plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 5 ways to get from Casper to Knoxville by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Casper (CPR) to Mcghee Tyson Airport (TYS)plane plane CPR - TYS
    7h 15m
    $288–1,085

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Casper (CPR) to Asheville Regional Airport (AVL)plane plane CPR - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h 58m
    $155–600

  3. Bus, train

    1. Take the bus from Casper 144 East A St to Denver Union Stationbus bus
    2. Take the train from Denver to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    2d 12h
    $923–1,710

  4. Bus

    1. Take the bus from Casper Amtrak Station to Cheyenne, WYbus bus
    2. Take the bus from Cheyenne to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d 14h
    $556–869

  5. Drive 1,480 mi

    1. Drive from Casper to Knoxvillecar car 1,480 mi
    25h 14m
    $271–391

Casper (CPR) to Mcghee Tyson Airport (TYS) flights

Calendar8Weekly Planes
Duration6h 47mAverage Duration
Ticket$220Cheapest Price
See schedules

Questions & Answers

Map of how to get from Casper to Knoxville.ExpandLaunch map view
  • Distance: 1,315.9 mi
  • Duration: 7h 15m

What companies run services between Casper, WY, USA and Knoxville, TN, USA?

United Airlines flies from Casper (CPR) to Mcghee Tyson Airport (TYS) once daily. Alternatively, you can take a bus from Casper Amtrak Station to Knoxville via Cheyenne, Denver Union Station, Chicago Bus Station, New York, NY, and Knoxville, TN in around 2d 14h.

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