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How to get fromCasper to Mayo Clinicby plane, bus, or car

Find Transport to Mayo Clinic

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There are 7 ways to get from Casper to Mayo Clinic by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Casper to Minneapolis–Saint Paul International Airport, bus

    best
    1. Fly from Casper (CPR) to Minneapolis–Saint Paul International Airport (MSP)plane plane CPR - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 50m
    $163–615

  2. Fly Casper to Rochester

    cheapest
    1. Fly from Casper (CPR) to Rochester (RST)plane plane CPR - RST
    9h 10m
    $104–505

  3. Bus

    1. Take the bus from Casper to Billingsbus bus
    2. Take the bus from Billings to Minneapolisbus bus
    3. Take the bus from Minneapolis to Rochesterbus bus
    26h 28m
    $317–432

  4. Drive  804.3 mi

    1. Drive from Casper to Mayo Cliniccar car 804.3 mi
    13h 8m
    $147–212

  5. Fly Casper to Fort Dodge Municipal Airport, drive

    1. Fly from Casper (CPR) to Fort Dodge Municipal Airport (FOD)plane plane CPR - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Mayo Cliniccar car
    8h 20m
    $118–485

  6. Drive to Rapid City, fly to Rochester

    1. Drive from Casper to Rapid-City-Airport-RAPcar car
    2. Fly from Rapid City (RAP) to Rochester (RST)plane plane RAP - RST
    10h 54m
    $113–478

  7. Drive to Rapid City, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Casper to Rapid-City-Airport-RAPcar car
    2. Fly from Rapid City (RAP) to Minneapolis–Saint Paul International Airport (MSP)plane plane RAP - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 10m
    $167–558

Casper to Mayo Clinic by bus and foot

Calendar1Weekly Services
Duration26h 28mAverage Duration
Ticket$317Cheapest Price
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Comparing Your Travel Options

Map of how to get from Casper to Mayo Clinic.ExpandLaunch map view
  • Distance: 766.4 mi
  • Duration: 7h 50m

What companies run services between Casper, WY, USA and Mayo Clinic, MN, USA?

You can take a bus from Casper to Mayo Clinic via Billings, Minneapolis, and Rochester in around 26h 28m. Alternatively, United Airlines, Delta, and American Airlines fly from Casper (CPR) to Rochester (RST) every 4 hours.

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