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How to get fromCayo Santa María to Santiago de Cubaby bus, train, car, or plane

Find Transport to Santiago de Cuba

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There are 5 ways to get from Cayo Santa María to Santiago de Cuba by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cayo Santa María to Santa Clarabus bus Santa Clara
    2. Take the bus from Santa Clara to Santiago de Cubabus bus Santa Clara
    12h 30m
    $14–26

  2. Bus, train

    cheapest
    1. Take the bus from Cayo Santa María to Santa Clarabus bus Santa Clara
    2. Take the train from Santa Clara to Santiago de Cubatrain train 11 / ...
    15h 39m
    $13–28

  3. Drive 618.9 km

    1. Drive from Cayo Santa María to Santiago de Cubacar car 618.9 km
    9h 9m
    $71–102

  4. Bus, fly

    1. Take the bus from Cayo Santa María to Santa Clarabus bus
    2. Fly from Abel Santamaría Airport (SNU) to Antonio Maceo International Airport (SCU)plane plane SNU - SCU
    23h 43m
    $109–495

  5. Bus via Las Tunas

    1. Take the bus from Cayo Santa María to Santa Clarabus bus
    2. Take the bus from Santa Clara to Las Tunasbus bus
    3. Take the bus from Las Tunas to Servicentro Martíbus bus
    13h 10m
    $38–156

Abel Santamaría Airport (SNU) to Antonio Maceo International Airport (SCU) flights

Calendar5Weekly Planes
Duration19h 30mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

Map of how to get from Cayo Santa María to Santiago de Cuba.ExpandLaunch map view
  • Distance: 712.9 km
  • Duration: 12h 30m

What companies run services between Cayo Santa María, Villa Clara, Cuba and Santiago de Cuba?

You can take a bus from Cayo Santa María to Santiago de Cuba via Santa Clara, Vc, and Santa Clara in around 12h 30m.

Airlines
Train operators
Bus operators

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