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How to get fromCayo Santa María to Holguínby bus, train, car, plane, or shuttle

Find Transport to Holguín

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There are 6 ways to get from Cayo Santa María to Holguín by bus, train, car, plane, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cayo Santa María to Santa Clarabus bus Santa Clara
    2. Take the bus from Santa Clara to Holguínbus bus Holguin
    10h 30m
    $13–24

  2. Bus, train

    1. Take the bus from Cayo Santa María to Santa Clarabus bus Santa Clara
    2. Take the train from Santa Clara to Holguintrain train 15
    13h 58m
    $13–26

  3. Drive  470.4 km

    1. Drive from Cayo Santa María to Holguíncar car 470.4 km
    7h 15m
    $55–80

  4. Bus, fly to Frank País International Airport

    1. Take the bus from Cayo Santa María to Santa Clarabus bus
    2. Fly from Abel Santamaría Airport (SNU) to Frank País International Airport (HOG)plane plane SNU - HOG
    27h 30m
    $116–590

  5. Bus via Holguin

    1. Take the bus from Cayo Santa María to Santa Clarabus bus Santa Clara
    2. Take the bus from Santa Clara to Holguinbus bus Santiago de Cuba parada en Guaimaro / ...
    12h 36m
    $38–66

  6. Bus, fly to Antonio Maceo International Airport, shuttle

    1. Take the bus from Cayo Santa María to Santa Clarabus bus
    2. Fly from Abel Santamaría Airport (SNU) to Antonio Maceo International Airport (SCU)plane plane SNU - SCU
    3. Take a shuttle bus from Melia Santiago de Cuba to Hotel Pernik Holguinshuttle bus
    25h 48m
    $175–818

Abel Santamaría Airport (SNU) to Frank País International Airport (HOG) flights

Calendar7Weekly Planes
Duration22h 50mAverage Duration
Ticket$93Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cayo Santa María to Holguín.ExpandLaunch map view
  • Distance: 582.9 km
  • Duration: 10h 30m

What companies run services between Cayo Santa María, Villa Clara, Cuba and Holguín, Cuba?

You can take a bus from Cayo Santa María to Holguín via Santa Clara, Vc, and Santa Clara in around 10h 30m.

Airlines
Train operators
Bus operators

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