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How to get fromCazenovia to Buffaloby train (Amtrak), bus (Flixbus, Greyhound), car, or plane

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There are 4 ways to get from Cazenovia to Buffalo by train (Amtrak), bus (Flixbus, Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Syracuse Regional Transportation Center to Buffalotrain train Empire Service / ...
    3h 25m
    $168–341

  2. Drive 168.3 mi

    cheapest
    1. Drive from Cazenovia to Buffalocar car 168.3 mi
    3h 6m
    $31–45

  3. Bus

    1. Take the bus from Syracuse Bus Station to Buffalobus bus FlixBus 2686 / ...
    3h 27m
    $153–201

  4. Fly

    1. Fly from Syracuse Hancock International Airport (SYR) to Buffalo Niagara International Airport (BUF)plane plane SYR - BUF
    5h 18m
    $274–948

Syracuse Hancock International Airport (SYR) to Buffalo Niagara International Airport (BUF) flights

Calendar108Weekly Planes
Duration5h 10mAverage Duration
Ticket$136Cheapest Price
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Questions & Answers

Map of how to get from Cazenovia to Buffalo.ExpandLaunch map view
  • Distance: 170 mi
  • Duration: 3h 25m

What companies run services between Cazenovia, NY, USA and Buffalo, NY, USA?

Amtrak operates a train from Syracuse Regional Transportation Center to Buffalo 3 times a day. Tickets cost $45–100 and the journey takes 2h 53m. VIA Rail also services this route once daily. Alternatively, FlixBus-us operates a bus from Syracuse Bus Station to Buffalo every 4 hours, and the journey takes 2h 55m. Five other operators also service this route.

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