There are 4 ways to get from Cazenovia to Buffalo by train (Amtrak), bus (Flixbus, Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Syracuse Regional Transportation Center to Buffalotrain Empire Service / ...
3h 25m$168–341Drive 168.3 mi
cheapest- Drive from Cazenovia to Buffalocar 168.3 mi
3h 6m$29–42Bus
- Take the bus from Syracuse Bus Station to Buffalobus FlixBus 2686 / ...
3h 37m$156–246Fly
- Fly from Syracuse Hancock International Airport (SYR) to Buffalo Niagara International Airport (BUF)plane SYR - BUF
5h 20m$288–1,097
Syracuse Hancock International Airport (SYR) to Buffalo Niagara International Airport (BUF) flights
Comparing Your Travel Options
The cheapest way to get from Cazenovia to Buffalo is to drive which costs $28 - $45 and takes 3h 6m.
The fastest way to get from Cazenovia to Buffalo is to drive which takes 3h 6m and costs $28 - $45.
No, there is no direct bus from Cazenovia station to Buffalo. However, there are services departing from Syracuse Bus Station and arriving at Buffalo via . The journey, including transfers, takes approximately 3h 37m.
No, there is no direct train from Cazenovia to Buffalo. However, there are services departing from Syracuse Regional Transportation Center and arriving at Buffalo via . The journey, including transfers, takes approximately 3h 25m.
The distance between Cazenovia and Buffalo is 171 miles. The road distance is 169.3 miles.
The best way to get from Cazenovia to Buffalo without a car is to train which takes 3h 25m and costs $160 - $350.
It takes approximately 3h 25m to get from Cazenovia to Buffalo, including transfers.
Cazenovia to Buffalo bus services, operated by Flixbus USA, depart from Syracuse Bus Station.
Cazenovia to Buffalo train services, operated by Amtrak, depart from Syracuse Regional Transportation Center station.
The best way to get from Cazenovia to Buffalo is to train which takes 3h 25m and costs $160 - $350. Alternatively, you can bus, which costs $150 - $250 and takes 3h 37m, you could also fly, which costs $280 - $1,100 and takes 5h 20m.
What companies run services between Cazenovia, NY, USA and Buffalo, NY, USA?
Amtrak operates a train from Syracuse Regional Transportation Center to Buffalo 3 times a day. Tickets cost $80–130 and the journey takes 2h 53m. VIA Rail also services this route once daily. Alternatively, Flixbus USA operates a bus from Syracuse Bus Station to Buffalo every 2 hours. Tickets cost $25–40 and the journey takes 3h 5m. Two other operators also service this route.
- Website
- delta.com
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $160–950
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 5h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–900
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $150–900
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $140–900
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h 3m
- When
- Friday and Saturday
- Estimated price
- $160–900
- Website
- united.com
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $160–900
- Website
- jetblue.com
Flights from Syracuse Hancock International Airport to Buffalo Niagara International Airport via Boston
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $170–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Buffalo
- Ave. Duration
- 2h 53m
- Frequency
- 3 times a day
- Estimated price
- $80–130
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Syracuse Regional Transportation Center to Buffalo
- Ave. Duration
- 2h 33m
- Frequency
- Once daily
- Estimated price
- $40–190
- Website
- VIA Rail
- Escape
- $40–110
- Business
- $70–180
- Business Plus
- $80–190
- Economy
- $40–120
- Economy Plus
- $45–120
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 5m
- Frequency
- Every 2 hours
- Estimated price
- $25–40
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h
- Frequency
- Every 3 hours
- Estimated price
- $29–45
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Syracuse Bus Station to Buffalo
- Saver
- $28–90
- Flexible
- $55–95
Want to know more about travelling around United States
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Booking & Getting There
Cazenovia to Buffalo bus services, operated by Flixbus USA, arrive at Buffalo station.
Cazenovia to Buffalo train services, operated by Amtrak, arrive at Buffalo station.
Yes, the driving distance between Cazenovia to Buffalo is 169 miles. It takes approximately 3h 6m to drive from Cazenovia to Buffalo.
There are 255+ hotels available in Buffalo.














