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How to get fromCdmx to Panama Cityby plane, bus, shuttle, or car

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There are 4 ways to get from Cdmx to Panama City by plane, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Benito Juárez International Airport

    best
    1. Fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY)plane plane MEX - PTY
    7h 8m
    $379–790

  2. Bus, shuttle

    cheapest
    1. Take the bus from México City to Tapachulabus bus
    2. Take a shuttle bus from Tapachula to Antigua Guatemalashuttle bus
    3. Take a shuttle bus from Antigua Guatemala to San Salvadorshuttle bus
    4. Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    2d 17h
    $285–387

  3. Drive  3,155.9 km

    1. Drive from Cdmx to Panama Citycar car 3,155.9 km
    45h 2m
    $429–620

  4. Fly from Felipe Ángeles International Airport

    1. Fly from Felipe Ángeles International Airport (NLU) to Tocumen International Airport (PTY)plane plane NLU - PTY
    11h 25m
    $590–1,242

Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) flights

Calendar57Weekly Planes
Duration4h 18mAverage Duration
Ticket$108Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cdmx to Panama City.ExpandLaunch map view
  • Distance: 2,447.6 km
  • Duration: 7h 8m

What companies run services between Cdmx, Mexico and Panama City, Panama?

Aeroméxico, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) every 4 hours.

Airlines
Bus operators

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Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from Heathrow Airport into central London, Travelling to and around Russia for the 2018 FIFA World Cup, and 10 amazing places to get away from it all in Australia - to help you get the most out of your next trip.