There are 4 ways to get from Cdmx to Panama City by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Benito Juárez International Airport
best- Fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY)plane MEX - PTY
7h 5m$279–590Fly from Felipe Ángeles International Airport
cheapest- Fly from Felipe Ángeles International Airport (NLU) to Tocumen International Airport (PTY)plane NLU - PTY
11h 14m$140–502Bus
- Take the bus from México City to Tapachulabus
- Take the bus from Tapachula to Guatemana Aguilar Batresbus
- Take the bus from Guatemala Aguilar Batres to Terminal San Carlos - Ticabusbus
- Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus
- Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus
2d 22h$200–295Drive 3,155.9 km
- Drive from Cdmx to Panama Citycar 3,155.9 km
45h 3m$432–624
Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) flights
Questions & Answers
The cheapest way to get from Cdmx to Panama City is to bus which costs $200 - $300 and takes 2 days 22h.
The fastest way to get from Cdmx to Panama City is to fly which takes 7h 5m and costs $270 - $600.
No, there is no direct bus from Cdmx to Panama City. However, there are services departing from Museo San Carlos and arriving at Terminal Tica Bus Panamá via México City, Tapachula, Guatemala Aguilar Batres, Terminal Tica Bus San Salvador and Terminal Tica Bus San José. The journey, including transfers, takes approximately 2 days 22h.
The distance between Cdmx and Panama City is 2448 km. The road distance is 3155.9 km.
The best way to get from Cdmx to Panama City without a car is to bus which takes 2 days 22h and costs $200 - $300.
It takes approximately 7h 5m to get from Cdmx to Panama City, including transfers.
Cdmx to Panama City bus services, operated by Autobuses Titanium, depart from México City station.
The best way to get from Cdmx to Panama City is to fly which takes 7h 5m and costs $270 - $600. Alternatively, you can bus, which costs $200 - $300 and takes 2 days 22h.
Cdmx to Panama City bus services, operated by Autobuses Titanium, arrive at Tapachula station.
Panama City is 1h ahead of Cdmx. It is currently 1:55 AM in Cdmx and 2:55 AM in Panama City.
What companies run services between Cdmx, Mexico and Panama City, Panama?
Aeroméxico, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) every 4 hours. Alternatively, you can take a vehicle from Cdmx to Terminal Tica Bus Panamá via Museo San Carlos, Mixcalco, México City, Tapachula, Guatemala Aguilar Batres, Terminal San Carlos - Ticabus, Terminal Tica Bus San Salvador, and Terminal Tica Bus San José in around 2d 22h.
- Website
- copaair.com
Flights from Benito Juárez International Airport to Tocumen International Airport
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $100–480
Flights from Felipe Ángeles International Airport to Tocumen International Airport via Cancun
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $100–460
Flights from Felipe Ángeles International Airport to Tocumen International Airport via Guadalajara
- Ave. Duration
- 9h 10m
- When
- Every day
- Estimated price
- $120–500
Flights from Felipe Ángeles International Airport to Tocumen International Airport via Havana
- Ave. Duration
- 6h 41m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $150–600
Flights from Felipe Ángeles International Airport to Tocumen International Airport via Monterrey
- Ave. Duration
- 7h 3m
- When
- Sunday
- Estimated price
- $130–550
Flights from Felipe Ángeles International Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 7h 19m
- When
- Monday, Wednesday, and Sunday
- Estimated price
- $190–550
- Phone
- +52 961 638 5018
- [email protected]
- Website
- autobusestitanium.com
Bus from México City to Tapachula
- Ave. Duration
- 15h
- Frequency
- 3 times a day
- Estimated price
- $45–70
- Schedules at
- autobusestitanium.com
- Book at
- autobusestitanium.com
- Delux
- $45–70
- First Class
- $50–60
Want to know more about travelling around the world?
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More Questions & Answers
Yes, the driving distance between Cdmx to Panama City is 3156 km. It takes approximately 45h 3m to drive from Cdmx to Panama City.
There are 885+ hotels available in Panama City.






