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How to get fromCdmx to Panama Cityby plane, bus, or car

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There are 5 ways to get from Cdmx to Panama City by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Benito Juárez International Airport

    best
    1. Fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY)plane plane MEX - PTY
    7h 5m
    $269–590

  2. Bus

    cheapest
    1. Take the bus from México City to Tapachulabus bus
    2. Take the bus from Tapachula to San Salvadorbus bus
    3. Take the bus from Terminal San Carlos - CCA to Terminal Atlántico Nortebus bus Sac
    4. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    2d 18h
    $206–296

  3. Drive 3,158.2 km

    1. Drive from Cdmx to Panama Citycar car 3,158.2 km
    45h 14m
    $432–625

  4. Fly from Felipe Ángeles International Airport

    1. Fly from Felipe Ángeles International Airport (NLU) to Tocumen International Airport (PTY)plane plane NLU - PTY
    10h 35m
    $350–992

  5. Bus via San Cristóbal de las Casas

    1. Take the bus from Terminal de Autobuses de Pasajeros de Oriente to San Cristóbal de las Casasbus bus
    2. Take the bus from San Cristóbal de las Casas to Panajachelbus bus
    3. Take the bus from Panajachel to San Salvadorbus bus
    4. Take the bus from San Salvador to San Josébus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    2d 20h
    $304–411

Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) flights

Calendar59Weekly Planes
Duration4h 22mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

Map of how to get from Cdmx to Panama City.ExpandLaunch map view
  • Distance: 2,447.6 km
  • Duration: 7h 5m

What companies run services between Cdmx, Mexico and Panama City, Panama?

Aeroméxico, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) every 4 hours. Alternatively, you can take a vehicle from Cdmx to Terminal Tica Bus Panamá via Balderas, Balbuena, México City, Tapachula, San Salvador, Terminal San Carlos - CCA, Terminal Atlántico Norte, and Terminal Tica Bus San José in around 2d 18h.

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