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How to get fromCentral Islip to Buffaloby train, plane, bus, or car

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There are 9 ways to get from Central Islip to Buffalo by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Central Islip to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    4h 41m
    $85–473

  2. Drive  402.5 mi

    cheapest
    1. Drive from Central Islip to Buffalocar car 402.5 mi
    8h 7m
    $74–107

  3. Train

    1. Take the train from Central Islip to New York Penn Stationtrain train Ronkonkoma Branch
    2. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    10h 35m
    $123–307

  4. Train, bus

    1. Take the train from Central Islip to New York Penn Stationtrain train Ronkonkoma Branch
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    10h 46m
    $78–137

  5. Train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Central Islip to Woodsidetrain train
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    5h 9m
    $106–630

  6. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Central Islip to New York Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    5h 35m
    $105–528

  7. Train to John F. Kennedy International Airport, fly to Rochester, bus

    1. Take the train from Central Islip to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Rochester (ROC)plane plane JFK - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 11m
    $128–621

  8. Train to Laguardia Airport, fly to Rochester, bus

    1. Take the train from Central Islip to Woodsidetrain train
    2. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 27m
    $144–818

  9. Bus

    1. Take the bus from Manorville to 86 St & Central Park Westbus bus Sag Harbor-Westbound / ...
    2. Take the bus from New York to Buffalobus bus Adt N816 / ...
    12h 52m
    $114–439

Central Islip to Buffalo by train

Calendar7Weekly Trains
Duration10h 35mAverage Duration
Ticket$123Cheapest Price
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Comparing Your Travel Options

Map of how to get from Central Islip to Buffalo.ExpandLaunch map view
  • Distance: 349.3 mi
  • Duration: 4h 41m

What companies run services between Central Islip, NY, USA and Buffalo, NY, USA?

You can take a train from Central Islip to Buffalo via New York Penn Station in around 10h 35m. Alternatively, you can take a train from Central Islip to Buffalo via Ronkonkoma, Islip Airport Connection, Manorville, 86 St & Central Park West, 86 St, 42 St-Port Authority Bus Terminal, and New York in around 12h 52m.

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