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How to get fromCentralia to Knoxvilleby taxi, plane, train, bus, or car

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There are 8 ways to get from Centralia to Knoxville by taxi, plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Midamerica St. Louis Airport, fly

    best
    1. Take the taxi from Centralia to Midamerica St. Louis Airport (BLV)taxi taxi
    2. Fly from Midamerica St. Louis Airport (BLV) to Mcghee Tyson Airport (TYS)plane plane BLV - TYS
    15h 1m
    $369–1,282

  2. Drive 430.5 mi

    cheapest
    1. Drive from Centralia to Knoxvillecar car 430.5 mi
    7h 8m
    $79–114

  3. Train, bus

    1. Take the train from Centralia Amtrak to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    39h 22m
    $551–1,067

  4. Train, bus via Indianapolis

    1. Take the train from Centralia Amtrak to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    39h 33m
    $359–599

  5. Train to Williamson County Regional Airport, fly

    1. Take the train from Centralia Amtrak to Carbondaletrain train
    2. Fly from Williamson County Regional Airport (MWA) to Mcghee Tyson Airport (TYS)plane plane MWA - TYS
    7h 25m
    $282–1,096

  6. Train, bus to Lambert–St. Louis International Airport, fly

    1. Take the train from Centralia Amtrak to Carbondaletrain train
    2. Take the bus from Carbondale to St. Louisbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    10h
    $219–1,004

  7. Train, bus via Ossining

    1. Take the train from Centralia Amtrak to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    39h 59m
    $506–944

  8. Train, bus #2

    1. Take the train from Centralia Amtrak to Carbondaletrain train
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    46h 3m
    $321–501

Midamerica St. Louis Airport (BLV) to Mcghee Tyson Airport (TYS) flights

Calendar5Weekly Planes
Duration15h 46mAverage Duration
Ticket$229Cheapest Price
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Questions & Answers

Map of how to get from Centralia to Knoxville.ExpandLaunch map view
  • Distance: 425.1 mi
  • Duration: 15h 1m

What companies run services between Centralia, IL, USA and Knoxville, TN, USA?

There is no direct connection from Centralia to Knoxville. However, you can take the taxi to Midamerica St. Louis Airport (BLV) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a train from Centralia Amtrak to Knoxville via Chicago Union Station, Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 39h 22m.

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