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How to get fromChampaign to Knoxvilleby plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

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There are 6 ways to get from Champaign to Knoxville by plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS)plane plane CMI - TYS
    5h 55m
    $213–892

  2. Drive  465.8 mi

    cheapest
    1. Drive from Champaign to Knoxvillecar car 465.8 mi
    8h 4m
    $85–123

  3. Bus

    1. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    35h 37m
    $322–482

  4. Train, bus

    1. Take the train from Champaign-Urbana to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    37h 59m
    $422–804

  5. Bus via Auburn Gresham

    1. Take the bus from Champaign Intermodal Trans Ctr to Chicagobus bus
    2. Take the bus from Chicago to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    36h 38m
    $342–511

  6. Bus, train

    1. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    38h 46m
    $442–832

University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS) flights

Calendar34Weekly Planes
Duration7h 4mAverage Duration
Ticket$145Cheapest Price
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Questions & Answers

Map of how to get from Champaign to Knoxville.ExpandLaunch map view
  • Distance: 392.5 mi
  • Duration: 5h 55m

What companies run services between Champaign, IL, USA and Knoxville, TN, USA?

American Airlines and United Airlines fly from University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS) 5 times a day. Alternatively, you can take a bus from Champaign Intermodal Trans Ctr to Knoxville via Indianapolis Union Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 35h 37m.

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